Maternal consumption of organic trace minerals alters calf systemic and neutrophil mRNA and microRNA indicators of inflammation and oxidative stress

Journal of Dairy Science
Carolina B JacometoJ J Loor

Abstract

Organic trace mineral (ORG) supplementation to dairy cows in substitution of sulfate (INO) sources has been associated with improvement in immune function during stressful states such as the peripartal period. However, the effect of supplemental ORG during pregnancy on the neonatal calf is unknown. Therefore, our aim was to investigate the effects of ORG supplementation during late pregnancy on the immune system and growth of the neonatal calf. Of specific interest was the evaluation of inflammation-related microRNA (miRNA) and target gene expression in blood neutrophils as indicators of possible nutritional programming. Forty multiparous cows were supplemented for 30d prepartum with 40 mg/kg of Zn, 20 mg/kg of Mn, 5 mg/kg of Cu, and 1mg/kg of Co from either organic (ORG) or sulfate (INO) sources (total diet contained supplemental 75 mg/kg of Zn, 65 mg/kg of Mn, 11 mg/kg of Cu, and 1 mg/kg of Co, and additional Zn, Mn, and Co provided by sulfates), and a subset of calves (n=8/treatment) was used for blood immunometabolic marker and polymorphonuclear leukocyte (PMNL) gene and miRNA expression analyses. Samples were collected at birth (before colostrum feeding), 1d (24 h after colostrum intake), and 7 and 21d of age. Data were an...Continue Reading

References

Dec 1, 1979·The Journal of Allergy and Clinical Immunology·G J Cropp
Jan 1, 1992·Annual Review of Nutrition·C H SmithV Ganapathy
Feb 16, 1991·The Veterinary Record·J G SkinnerL Roberts
Jan 1, 1981·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·M E TolbertG D Draper
Jan 23, 1999·Methods in Enzymology·G Cao, R L Prior
Jul 14, 2000·Physiological Reviews·D B Shennan, M Peaker
Jul 3, 2003·Journal of Dairy Science·C E OntsoukaJ W Blum
Oct 21, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ian SabroeMoira K B Whyte
Jan 21, 2006·Journal of Animal Physiology and Animal Nutrition·J W Blum
Aug 4, 2006·Proceedings of the National Academy of Sciences of the United States of America·Konstantin D TaganovDavid Baltimore
Jan 24, 2007·Proceedings of the National Academy of Sciences of the United States of America·Ryan M O'ConnellDavid Baltimore
Apr 7, 2007·The Veterinary Journal·Toomas OrroTimo Soveri
May 18, 2007·Annual Review of Nutrition·Bo Lönnerdal
Jun 22, 2007·Placenta·H N JonesT Jansson
Oct 4, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Esmerina TiliCarlo Maria Croce
Jan 15, 2008·Cell·Ana EulalioElisa Izaurralde
Mar 8, 2008·The Veterinary Journal·Jerry W Spears, William P Weiss
Mar 20, 2008·Clinical & Developmental Immunology·Isabelle WolowczukCorinne Grangette
Mar 18, 2009·Proceedings of the National Academy of Sciences of the United States of America·Flavia BazzoniMassimo Locati
Mar 6, 2010·The Proceedings of the Nutrition Society·L AttigC Junien
Apr 10, 2010·Journal of Applied Physiology·Oscar AguileraMario F Fraga
Apr 15, 2010·British Poultry Science·Y M BaoK Bruerton
Jul 14, 2010·The Veterinary Journal·P D Eckersall, R Bell
Dec 27, 2011·Research in Veterinary Science·E TrevisiG Bertoni
Aug 10, 2012·American Journal of Perinatology·Haiyan ChenLaurie J Moyer-Mileur
Jan 17, 2013·Journal of Leukocyte Biology·Michael P Gantier
Feb 19, 2013·Current Opinion in Clinical Nutrition and Metabolic Care·Elvira LarquéBerthold Koletzko

❮ Previous
Next ❯

Citations

Nov 21, 2017·Journal of Dairy Science·A F KertzJ K Drackley
Aug 31, 2020·Journal of Animal Science and Biotechnology·Vincenzo LopreiatoErminio Trevisi
Jun 3, 2018·Animals : an Open Access Journal From MDPI·Javier FrutosFrancisco Javier Giráldez
Nov 2, 2019·Research in Veterinary Science·Valeria Maria MorittuVincenzo Lopreiato
Nov 11, 2019·Veterinary Immunology and Immunopathology·Amelia R Hofstetter, Randy E Sacco
Dec 10, 2020·Journal of Animal Science and Biotechnology·Johan S Osorio
May 1, 2021·Animals : an Open Access Journal From MDPI·Kelsey Margaret HarveyRodrigo da Silva Marques
Oct 9, 2021·Journal of Animal Physiology and Animal Nutrition·Damiano CavalliniAndrea Formigoni

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.