Abstract
To identify maternal deaths due to sepsis in the state of Michigan, review the events leading to diagnosis, and evaluate treatment to identify areas for improvement. A case series was collected for maternal deaths due to sepsis from a cohort of maternal deaths in the state of Michigan. The study period was 1999-2006 and included deaths during pregnancy and up to 42 days postpartum. Cases were identified using Maternal Mortality Surveillance records from the Michigan Department of Community Health. Each case was reviewed by all authors. Maternal sepsis was the cause of death in 15% (22/151) of pregnancy-related deaths. Of 22 deaths, 13 women presented to the hospital with sepsis, two developed sepsis during hospitalization, and seven developed sepsis at home without admission to the hospital for care. Review of available hospital records (n=15) revealed delays in initial appropriate antibiotic treatment occurred in 73% (11/15) of patients. Delay in escalation of care also occurred and was identified in 53% (8/15) of patients. Common elements in these deaths illustrate three key delays that may have contributed to the deaths: in recognition of sepsis, in administration of appropriate antibiotics, and in escalation of care. III.
References
Jun 1, 1992·Chest·R C BoneW J Sibbald
Jan 17, 2002·The New England Journal of Medicine·E RiversUNKNOWN Early Goal-Directed Therapy Collaborative Group
Oct 23, 2003·Southern Medical Journal·Zuber D MullaSteven T Wiersma
Apr 20, 2004·Critical Care Medicine·R Phillip DellingerUNKNOWN Surviving Sepsis Campaign Management Guidelines Committee
Apr 26, 2005·The Journal of Antimicrobial Chemotherapy·David L PatersonJoseph W Chow
Apr 21, 2006·Critical Care Medicine·Anand KumarMary Cheang
May 26, 2007·Anesthesiology·Jill M MhyreNorah N Naughton
Jan 22, 2009·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists
Apr 17, 2012·Internal Medicine·Tsuneaki KenzakaMasayoshi Hashimoto
Jan 29, 2013·Critical Care Medicine·R Phillip DellingerUNKNOWN Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup
Sep 12, 2013·Anesthesia and Analgesia·Melissa E BauerJill M Mhyre
May 3, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jonathan R CarapetisRoss Andrews
Jun 21, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Dennis L StevensJames C Wade
Aug 28, 2014·Obstetrics and Gynecology·Melissa E BauerDavid M Aronoff
Sep 10, 2014·Obstetrics and Gynecology·Jill M MhyreMary E DʼAlton
Citations
Oct 30, 2016·International Journal of Obstetric Anesthesia·G AbirB Carvalho
Nov 7, 2016·Obstetrics and Gynecology Clinics of North America·Lauren A Plante
Feb 18, 2017·Anesthesia and Analgesia·Philip E Hess
Apr 7, 2017·Obstetrics and Gynecology·Ali AlhousseiniManasi Patwardhan
Mar 17, 2017·MCN. the American Journal of Maternal Child Nursing·Sheryl E ParfittCheryl Roth
Sep 9, 2017·Obstetrics and Gynecology·Sarah Rae EasterLaura E Riley
Sep 9, 2017·Obstetrics and Gynecology·Catherine M AlbrightBrenna L Hughes
Jan 31, 2016·The Journal of Perinatal & Neonatal Nursing·Catherine M AlbrightBrenna L Hughes
Feb 23, 2019·Current Opinion in Obstetrics & Gynecology·Megan E Foeller, Ronald S Gibbs
Sep 1, 2018·Anesthesia and Analgesia·Melissa E BauerBrian T Bateman
Apr 26, 2019·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists' Committee on PracticeBulletins—Obstetrics
Jan 31, 2016·Current Opinion in Obstetrics & Gynecology·Lavi Oud
Dec 12, 2017·Obstetric Medicine·Tabassum Firoz, Susannah L Woodd
Nov 7, 2019·Medicine·Ruiqi DuanHaiyan Yu
Aug 21, 2019·Journal of Clinical Medicine·Kuan-Sheng Lee, Jian-Pei Huang
Jun 11, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Lavi Oud
Nov 20, 2019·Anesthesia and Analgesia·Melissa E BauerBrian T Bateman
Apr 30, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Inshirah SgayerMaya Frank Wolf
Dec 18, 2020·Medicine·Ana Maria Coêlho HolandaLeila Katz
Mar 21, 2019·Gynécologie, Obstétrique, Fertilité & Sénologie·K FaureD Subtil
May 1, 2021·Current Opinion in Anaesthesiology·Gillian Abir, Melissa E Bauer
Jul 9, 2021·Obstetrics and Gynecology·Andrea ShieldsTorre Halscott
Jul 25, 2021·BMC Pregnancy and Childbirth·Nouf AbutheraaAlexander B Mullen
Oct 12, 2021·American Journal of Perinatology·Angela J StephensBaha M Sibai