Maternal experience and adult neurogenesis in mammals: Implications for maternal care, cognition, and mental health.

Journal of Neuroscience Research
Joanna Medina, Joanna L Workman

Abstract

The transition to motherhood encompasses physiological and behavioral adaptations essential for the initiation and maintenance of offspring care and feeding and includes widespread changes throughout the brain. The growth of new neurons occurs across the lifespan in distinct regions of mammalian brains and changes dynamically across reproductive events in female mammals. The subventricular zone (SVZ) and dentate gyrus (DG) of the hippocampus undergo high rates of neurogenesis in adulthood and are sensitive to hormonal fluctuations. Pregnancy and the postpartum period are associated with increased cell proliferation in the SVZ and interneuron survival in the olfactory bulb. In mice, peripartum prolactin signaling mediates SVZ neurogenesis and is important for enhanced olfactory recognition of offspring and maternal care. In contrast, cell proliferation and immature neuron survival decrease in the DG during the postpartum period. High baseline glucocorticoid concentrations suppress hippocampal neurogenesis, potentially representing an energetic trade-off accompanying a reduced need for spatial navigation early postpartum. In women, hippocampal volume decline during pregnancy and partial recovery during the postpartum period could...Continue Reading

References

Jul 1, 1978·Physiology & Behavior·L J Terlecki, R S Sainsbury
Jan 1, 1992·Endocrinology·C D WalkerM F Dallman
Jun 12, 1992·Annals of the New York Academy of Sciences·S L Lightman
Mar 1, 1991·The American Journal of Psychiatry·M SerbyD Kalkstein
Jan 1, 1988·Psychoneuroendocrinology·J S RosenblattA L Giordano
Sep 1, 1988·Biology of Reproduction·C H Kinsley, R S Bridges
Mar 1, 1969·The American Journal of Physiology·J L VoogtJ Meites
Jun 1, 1967·Journal of Comparative and Physiological Psychology·D P KimbleC W Hendrickson
Mar 24, 1997·The Journal of Comparative Neurology·G SimićN Bogdanović
Nov 11, 1998·Nature Medicine·P S ErikssonF H Gage
Mar 31, 1999·Psychoneuroendocrinology·J G BuckwalterT M Goodwin
Feb 1, 2000·Journal of Cellular Physiology·T Scholzen, J Gerdes
Feb 26, 2000·Science·F H Gage
Mar 14, 2000·Hormones and Behavior·L A GaleaM T Phelps
Jun 15, 2001·The Journal of Comparative Neurology·H A Cameron, R D McKay
Nov 28, 2001·The European Journal of Neuroscience·M BanasrA Daszuta
Feb 28, 2002·BMC Psychiatry·Karin Gutiérrez-LobosHeinz Katschnig
Mar 19, 2002·Journal of Neuroscience Methods·N KeeJ M Wojtowicz
May 2, 2003·The Journal of Neuropsychiatry and Clinical Neurosciences·Robert N McLayConstantine G Lyketsos
Oct 24, 2003·The Journal of Comparative Neurology·Jason P BrownH Georg Kuhn
Aug 25, 2004·Hormones and Behavior·F LévyP Poindron
Jan 19, 2005·The European Journal of Neuroscience·Sebastien Couillard-DespresLudwig Aigner
May 3, 2005·Brain Research. Developmental Brain Research·Miyako Furuta, Robert S Bridges
Jun 29, 2005·Brain Research Bulletin·Jessica D GatewoodCraig Howard Kinsley

❮ Previous
Next ❯

Citations

May 21, 2020·Journal of Neuroscience Research·Inger Sundström Poromaa
May 18, 2019·Neural Plasticity·Lily WanXiao-Xin Yan
Nov 22, 2020·Archives of Women's Mental Health·Harish Thippeswamy, William Davies
Jan 23, 2021·Developmental Psychobiology·Nathan D HorrellWendy Saltzman
Apr 20, 2021·General and Comparative Endocrinology·Pamela ParéMaria Cátira Bortolini
Dec 6, 2021·Neuroscience and Biobehavioral Reviews·Jodi L PawluskiJoseph S Lonstein
Jan 13, 2022·Neural Regeneration Research·Ana R Costa-BritoCecília R A Santos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Molecular Neurobiology
Itaru Imayoshi, Ryoichiro Kageyama
Development, Growth & Differentiation
Itaru ImayoshiRyoichiro Kageyama
© 2022 Meta ULC. All rights reserved