Maternal immunization to modulate the development of allergic response and pathogen infections

Immunotherapy
Paula Ordonhez RigatoMaria Notomi Sato

Abstract

This article reviews recent experimental approaches of preventive strategies regarding allergy and infections by pathogens, particularly in early childhood, by targeting maternal immunomodulation. Basic research is essential to understand maternal vaccination as a strategy to control allergic disease and bacterial and viral infections; thus, providing support for future translational research. The environmental stimuli and host genetic factors, along with maternal influences in early life when immune systems are developing and during postnatal life, are essential for the decision between tolerance induction or allergen sensitization. Maternal immunomodulation strategies should serve as a challenge when attempting to halt the spread of allergy responses and viral infections, until the innate and adaptive arms of the immune system of the neonates are competent.

References

Jul 28, 1979·Lancet·U M SaarinenM A Siimes
Jan 1, 1989·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G HattevigN I Kjellman
May 1, 1987·Acta paediatrica Scandinavica·R TronconeS Auricchio
Oct 6, 1984·Lancet·E E Jarrett
Nov 1, 1983·Human Immunology·N ReinsmoenF H Bach
Jun 1, 1984·Immunological Reviews·N K Jerne
Apr 1, 1981·The Journal of Experimental Medicine·J HiernauxP J Baker
Jan 1, 1994·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·D M Fergusson, L J Horwood
Feb 1, 1994·Archives of Pediatrics & Adolescent Medicine·P G SzilagyiL E Rodewald
Jan 1, 1993·International Archives of Allergy and Immunology·M P PiccinniS Romagnani
Aug 1, 1996·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·A C JonesJ A Warner
Aug 9, 1997·Lancet·J S AlmA Scheynius
Dec 31, 1997·The Journal of Clinical Investigation·E ManickanB T Rouse
Jan 1, 1997·Pediatric Pulmonology. Supplement·S M TariqD W Hide
Jul 24, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C A JonesJ O Warner
Jan 13, 1999·Clinical Immunology : the Official Journal of the Clinical Immunology Society·J D BoyerD B Weiner
Mar 3, 1999·Proceedings of the National Academy of Sciences of the United States of America·M C KarlssonB Heyman
Jun 5, 1999·Reviews of Reproduction·F SajiM Koyama
Jan 7, 2000·Pediatric Research·M F BöttcherB Björkstén
Jan 19, 2000·Immunology Today·S Marshall-ClarkeJ Hassan
Aug 10, 2000·Nature Medicine·V GerdtsP J Griebel

❮ Previous
Next ❯

Citations

Aug 3, 2012·Immunotherapy·Maria Notomi Sato
Sep 16, 2014·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Aline Aparecida de Lima LiraJefferson Russo Victor
Apr 26, 2017·Human Vaccines & Immunotherapeutics·Fábio da Ressureição SgnottoJefferson Russo Victor
Jan 23, 2018·International Journal of Dermatology·Fábio D R SgnottoJefferson R Victor
Nov 13, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Fábio da Ressureição SgnottoJefferson Russo Victor
Apr 22, 2017·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Marília Garcia de OliveiraJefferson Russo Victor
Aug 8, 2018·Allergologia et immunopathologia·Aline Aparecida de Lima LiraJefferson Russo Victor

❮ Previous
Next ❯

Methods Mentioned

BETA
transfection

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.