Maternal Instruction About Jaundice and the Incidence of Acute Bilirubin Encephalopathy in Nigeria

The Journal of Pediatrics
Richard P WennbergCarlos D Coda-Zabetta

Abstract

To evaluate whether teaching mothers about neonatal jaundice will decrease the incidence of acute bilirubin encephalopathy among infants admitted for jaundice. This was a multicenter, before-after and cross-sectional study. Baseline incidences of encephalopathy were obtained at 4 collaborating medical centers between January 2014 and May 2015 (Phase 1). Structured jaundice instruction was then offered (May to November 2015; Phase 2) in antenatal clinics and postpartum. Descriptive statistics and logistic regression models compared 3 groups: 843 Phase 1 controls, 338 Phase 2 infants whose mothers received both antenatal and postnatal instruction (group A), and 215 Phase 2 infants whose mothers received no instruction (group B) either because the program was not offered to them or by choice. Acute bilirubin encephalopathy occurred in 147 of 843 (17%) Phase 1 and 85 of 659 (13%) Phase 2 admissions, which included 63 of 215 (29%) group B and 5 of 338 (1.5%) group A infants. OR for having acute bilirubin encephalopathy, comparing group A and group B infants adjusted for confounding risk factors, was 0.12 (95% CI 0.03-0.60). Delayed care-seeking (defined as an admission total bilirubin ≥18 mg/dL at age ≥48 hours) was the strongest si...Continue Reading

References

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Jan 31, 2017·The Journal of Pediatrics·Salma Z El HouchiRichard P Wennberg
Jun 13, 2017·Journal of Tropical Pediatrics·Zubaida Ladan FaroukTina M Slusher
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Aug 30, 2017·Current Pediatric Reviews·Richard P WennbergSteven M Shapiro
Mar 30, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Udochukwu M DialaUNKNOWN *On behalf of the Stop Kernicterus In Nigeria (SKIN) study group

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Citations

Dec 29, 2020·Seminars in Perinatology·Zubaida L FaroukAngela Okolo
Jan 12, 2021·Global Pediatric Health·Ogundare Ezra OlatundeOlatunya Oladele Simeon
Mar 21, 2021·Journal of Tropical Pediatrics·Zubaida L FaroukIda L Slusher

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