Maternal mortality due to cardiac disease in low- and middle-income countries

Tropical Medicine & International Health : TM & IH
Steffie HeemelaarThomas van den Akker

Abstract

To assess the frequency of maternal death (MD) due to cardiac disease in low- and middle-income countries (LMIC). Systematic review searching Medline, EMBASE, Web of Science, Cochrane Library, Emcare, LILACS, African Index Medicus, IMEMR, IndMED, WPRIM, IMSEAR up to 01/Nov/2017. Maternal mortality reports from LMIC reviewing all MD in a given geographical area were included. Hospital-based reports or those solely based on verbal autopsies were excluded. Numbers of MD and cardiac-related deaths were extracted. We calculated cardiac disease MMR (cMMR, cardiac-related MD/100 000 live births) and proportion of cardiac-related MDs among all MDs. Frequency of cardiac MD was compared with the MMR of the country. Forty-seven reports were included, which reported on 38,486 maternal deaths in LMIC. Reported cMMR ranged from 0/100 000 live births (Moldova, Ghana) to 31.9/100 000 (Zimbabwe). The proportion of cardiac-related MD ranged from 0% (Moldova, Ghana) to 24.8% (Sri Lanka). In countries with a higher MMR, cMMR was also higher. However, the proportion of cardiac-related MD was higher in countries with a lower MMR. The burden of cardiac-related mortality is difficult to assess due limited availability of mortality reports. The proport...Continue Reading

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Citations

Jun 3, 2021·Current Treatment Options in Cardiovascular Medicine·Henrietta A AfariAmy A Sarma

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