Maternal obesity and the risk of fetal acidosis at birth

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Inmaculada Cardona-BenavidesSebastián Manzanares Galán

Abstract

Background: Maternal obesity is a risk factor for multiple obstetrics complications and adverse outcomes. The objective of the study was to investigate the association between obesity (IMC >30) and fetal acidosis at birth.Methods and findings: This hospital-based cohort study was based on 24,307 live-born infants in which maternal body mass index (BMI) information was available and delivered in the Granada north region during 2007-2018 from data of the Hospital Medical Birth Registry. Multivariate using logistic regression was performed to assess the association between fetal acidosis and BMI, crude, and adjusted odds ratio of fetal acidosis were calculated. p < .05 was considered statistically significant. We adjusted by maternal age, parity, hypertension, diabetes, and smoking habits. In the study population of 17,167 term live births, 518 infants (3.02%) had an umbilical cord blood pH < 7.10. The obesity rate in mothers with acidosis at delivery was 12.7%, but morbid obesity rate was 2.51% (adjusted OR 1.82).Conclusion: This study strengthens the evidence that demonstrates that morbid obesity is an independent risk factor for fetal acidosis at birth.

References

Sep 1, 1979·British Journal of Obstetrics and Gynaecology·T Weber, S Hahn-Pedersen
Sep 1, 1989·American Journal of Obstetrics and Gynecology·J A ThorpR K Creasy
May 1, 2004·American Journal of Obstetrics and Gynecology·Joshua L WeissFASTER Research Consortium
Nov 2, 2004·Obstetrics and Gynecology·Anjel VahratianAnna Maria Siega-Riz
Sep 13, 2006·Archives of Gynecology and Obstetrics·Haim A AbenhaimRobert Usher
Sep 11, 2007·American Journal of Obstetrics and Gynecology·Susan Y ChuKathryn M Curtis
Jan 22, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·HAPO Study Cooperative Research Group
Feb 4, 2011·American Journal of Obstetrics and Gynecology·Patrick M Catalano, Sylvie Hauguel-de Mouzon
Apr 19, 2011·Early Human Development·Sergio FerrazzaniAlessandro Caruso
May 28, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Galán Sebastián ManzanaresVallejo José Luis Gallo
Jul 30, 2011·American Journal of Obstetrics and Gynecology·Michelle A KominiarekJudith U Hibbard
Mar 1, 2012·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·U A RajaS Sharma
Feb 26, 2013·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Everett F MagannJohn C Morrison
Aug 24, 2013·Obstetrics and Gynecology·Rodney K EdwardsAlan T N Tita
Mar 4, 2015·American Journal of Obstetrics and Gynecology·Luciana LassanceSylvie Hauguel-de Mouzon
Feb 10, 2017·BMJ : British Medical Journal·Patrick M Catalano, Kartik Shankar
Jun 21, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Francesca CrovettoBarbara Acaia
Jun 24, 2017·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Sônia Regina Cabral MadiJosé Mauro Madi
Jun 20, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Stefan JohanssonSven Cnattingius
Oct 2, 2018·The Journal of Pediatrics·Sarah-Jane ParkerYvonne W Wu

Related Concepts

Acidosis
Birth
Diabetes
Hypertensive Disease
Obesity
Obesity, Morbid
Parity
Umbilical Cord Blood
Logistic Regression
Maternal Obesity Syndrome

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.

Related Papers

International Journal of Obstetric Anesthesia
Banu CevikSerhan Colakoğlu
International Journal of Obstetric Anesthesia
Tanya Jones
International Journal of Obstetric Anesthesia
Olubukola Nafiu
Birth Defects Research. Part A, Clinical and Molecular Teratology
Marie I Blomberg, Bengt Källén
Journal of Perinatology : Official Journal of the California Perinatal Association
H AlyA El-Mohandes
© 2021 Meta ULC. All rights reserved