Maternal serum split and hairy-related protein 1 in preeclampsia versus normal pregnancy.

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Thanisa Kitjaras, Vorapong Phupong

Abstract

The primary objective was to compare maternal serum split and hairy related protein-1 (SHARP1) in preeclamptic women versus normal pregnant women. The secondary objectives were to compare maternal and neonatal outcomes between preeclampsia and normal pregnant women. This cross-sectional analytic study included 75 preeclamptic pregnant women and 75 normal pregnant women at Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital between March 2018 and May 2019. Blood was collected into nonheparinized tubes. Blood samples were centrifuged and stored at -80 °C until assayed. Maternal serum SHARP1 levels were measured by enzyme-linked immunosorbent assays. Maternal and neonatal outcomes were recorded. Median serum SHARP1 level in preeclampsia was significantly higher than in normal pregnancy (5.2 vs. 3.7 ng/mL, p = .007). Preeclamptic women had a higher rate of cesarean section than normal pregnant women (68% vs. 32%, p < .001). Preeclamptic women had lower neonatal birth weight than normal pregnant women (2,546.1 ± 766.3 vs 2,884.5 ± 479.9, p = .001). Neonatal complications were higher in preeclamptic women than normal pregnant women (40% vs. 17.3%, p = .002). ...Continue Reading

References

Apr 4, 2006·Lancet·Khalid S KhanPaul Fa Van Look
Feb 1, 2008·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Fuyuki SatoHiroshi Kijima
Jun 12, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Edgardo AbalosLale Say
Sep 25, 2014·Current Topics in Developmental Biology·Jin Rong OwReshma Taneja
Sep 8, 2015·Lancet·Ben W J MolG Justus Hofmeyr
Nov 16, 2016·Journal of Perinatal Medicine·Ali Ozgur ErsoyNuri Danisman
Jul 17, 2019·BMJ : British Medical Journal·Graham J BurtonAshley Moffett
Aug 24, 2019·Scientific Reports·Noppakorn Prakansamut, Vorapong Phupong

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