Maternal smoking during pregnancy and postnatal exposure to environmental tobacco smoke as predisposition factors to acute respiratory infections

Environmental Health Perspectives
W Jedrychowski, E Flak

Abstract

This study compared susceptibility to respiratory morbidity in a cohort of 9-year-old children exposed congenitally and postnatally to environmental tobacco smoke (ETS) to susceptibility in a cohort of unexposed children. The epidemiologic study included 1129 children: 594 boys and 535 girls attending the second grade of grammar schools in Kraków, Poland. We found strong evidence that children exposed to ETS in their homes were more susceptible to acute respiratory tract illnesses than unexposed children. A dose-response relationship between degree of exposure [for lower ETS exposure, odds ratio (OR) = 1.32; for higher ETS exposure, OR = 1.74] supports a causal explanation for the association observed. The significant trend of increased risk of respiratory infections due to ETS level in nonatopic children whose mothers did not smoke cigarettes during pregnancy suggests a direct effect of ETS exposure on the child's respiratory health. ETS combined with allergy nearly tripled the risk of acute respiratory tract illness (OR = 3.39; 95% CI, 1.93-5.93), and maternal smoking during pregnancy had a modifying effect on the risk of respiratory illnesses due to ETS after accounting for atopy. The stronger effect of ETS in atopic childre...Continue Reading

References

Feb 1, 1978·Archives of Disease in Childhood·M BlandM H Banks
Dec 1, 1976·British Journal of Preventive & Social Medicine·S R LeederW W Holland
Jan 1, 1976·Chest·M D Lebowitz, B Burrows
Feb 1, 1992·International Journal of Epidemiology·F ForastiéreC A Perucci
Jan 1, 1992·The American Review of Respiratory Disease·E J Pérez-StableN L Benowitz
Sep 1, 1990·Journal of Epidemiology and Community Health·A WoodwardH Miles
Dec 1, 1989·International Journal of Epidemiology·C G VictoraS C Fuchs
Sep 1, 1988·The American Review of Respiratory Disease·F D MartinezR Ronchetti
Apr 1, 1988·The American Review of Respiratory Disease·D B CoultasJ M Samet
Aug 1, 1988·American Journal of Obstetrics and Gynecology·J E HaddowJ E McCarthy
Aug 1, 1987·Archives of Disease in Childhood·B Taylor, J Wadsworth
Apr 1, 1986·The Journal of Allergy and Clinical Immunology·A B Murray, B J Morrison
Jun 1, 1969·The Journal of Allergy·P CameronJ Winton
Jan 15, 1995·American Journal of Epidemiology·J J Stoddard, T Miller

❮ Previous
Next ❯

Citations

Mar 29, 2014·American Journal of Respiratory Cell and Molecular Biology·Yuan XuLars-Olaf Cardell
Sep 17, 2005·American Journal of Respiratory and Critical Care Medicine·Madé WentenFrank D Gilliland
Jul 20, 2007·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Thomas KovesiJ David Miller
May 13, 2010·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Lin CorsonRachel L Miller
Dec 13, 2002·Patient Education and Counseling·Debra P BonolloJudith K Ockene
Dec 8, 2000·Journal of Addictive Diseases·N T Laughlin
Oct 23, 2012·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Michael S BusinelleDavid W Wetter
Mar 21, 2009·European Journal of Pediatrics·Maria Cheraghi, Sundeep Salvi
Nov 8, 2007·Inhalation Toxicology·Jonathan Ciencewicki, Ilona Jaspers
Nov 19, 2013·American Journal of Preventive Medicine·Emara Nabi-BurzaSusan Regan
Mar 7, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Paul NoakesSusan L Prescott
Mar 5, 2013·Environment International·Sylwia NarkowiczJacek Namieśnik
Oct 14, 2009·Archivos de bronconeumología·Bibiana FrígulsOriol Vall
Feb 19, 2008·Paediatric Respiratory Reviews·Susan L Prescott
May 20, 1999·Human & Experimental Toxicology·E Dybing, T Sanner
Dec 28, 2000·Journal of Occupational and Environmental Medicine·A M Ducatman, R K McLellan
Mar 21, 2018·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tariq A BhatYasmin Thanavala
Sep 18, 2015·Clinical and Vaccine Immunology : CVI·Cosby A Stone, E Kathryn Miller
Sep 10, 2005·European Journal of Epidemiology·Renata Zlotkowska, Jan E Zejda
Dec 27, 2005·The Pediatric Infectious Disease Journal·Fraser Brims, Anoop J Chauhan
May 6, 1999·Current Opinion in Pulmonary Medicine·D A Enarson, J Chretien
Feb 6, 2004·British Medical Bulletin·Junfeng Zhang, Kirk R Smith
Oct 26, 2012·Academic Medicine : Journal of the Association of American Medical Colleges·Phillip Kum-NjiLori Keyser-Marcus
Mar 15, 2007·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Susan L Prescott, Paul S Noakes
Feb 7, 2019·The Journal of Pediatrics·Laura S KorhonenHasse Karlsson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.