PMID: 3752421May 1, 1986Paper

Maternal smoking leads to increased cord serum IgG3

Allergy
C G Magnusson, S G Johansson

Abstract

IgG subclass levels in cord serum of unselected European newborns were studied in relation to parental smoking. Cord IgG3 was significantly (P less than 0.01) higher in newborns of smoking mothers (n = 18; geom.mean = 87.0%) compared to those of non-smoking mothers (n = 66; geom.mean = 61.0%). Maternal smoking did not influence (P greater than 0.10) cord IgG2 or cord IgG4. Paternal smoking did not affect any of the three immunoglobulins in cord serum (P greater than 0.10). These data suggest that tobacco smoking affects IgG3 synthesis in some direct or indirect way.

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Citations

Apr 1, 1997·Journal of the American Academy of Dermatology·T SchäferK Uberla
Jan 1, 1997·Allergy·T Schäfer, J Ring
Jan 1, 1994·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·S Halken
Jan 20, 2009·Allergologia et immunopathologia·M Morales Suárez-VarelaN Gimeno Clemente
Dec 25, 2016·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Nikhita ChahalEdwina H Yeung
Jan 5, 2007·Revue des maladies respiratoires·E Bosdure, J C Dubus

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