Maternal supplementation with CLA decreases milk fat in humans

Lipids
Nicole MastersMichelle K McGuire

Abstract

CLA refers to isomers of octadecadienoic acid with conjugated double bonds. The most abundant form of CLA (rumenic acid (RA): c9,t11-18:2) is found in milk and beef fat. Further, CLA supplements containing RA and t10,c12-18:2 are now available. Consumption of commercially produced CLA has been shown to decrease adipose accretion in growing laboratory and production animals and cause milk fat depression in cows. We tested the hypothesis that CLA supplementation would increase milk CLA concentration and decrease milk fat content in humans. Breastfeeding women (n = 9) participated in this double-blind, placebo-controlled, crossover study divided into three periods: intervention I (5 d), washout (7 d), and intervention II (5 d). Women were randomized to treatment order. During each intervention period, women consumed 1.5 g of CLA supplement or placebo (olive oil) daily; during the washout period, no supplements were consumed. Milk was collected by complete breast expression on the final day of each period; milk output was estimated by 24-h weighing on the penultimate day of each intervention period. Milk RA and t10,c12-18:2 concentrations were greater (P < 0.05) during the CLA treatment period as compared to the placebo period. Mil...Continue Reading

References

Aug 1, 1990·The Journal of Nutrition·B B TeterM Keeney
Aug 1, 1980·Journal of Dairy Science·D R Selner, L H Schultz
Jul 1, 1994·Atherosclerosis·K N LeeM W Pariza
Jun 1, 1997·The Journal of Nutrition·P W Parodi
Mar 21, 1998·The Journal of Nutrition·P E HartmannL R Mitoulas
Apr 16, 1998·Biochemical and Biophysical Research Communications·K L HouseknechtM A Belury
Jun 11, 1998·Journal of Dairy Science·J M GriinariK V Nurmela
Jan 25, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·L H BaumgardD E Bauman

❮ Previous
Next ❯

Citations

Feb 19, 2008·The British Journal of Nutrition·Alexandra SchmidRobert Sieber
Sep 26, 2003·The Proceedings of the Nutrition Society·Michael J Azain
Mar 29, 2012·Critical Reviews in Food Science and Nutrition·Allison Dilzer, Yeonhwa Park
Aug 1, 2012·Polish Journal of Veterinary Sciences·J OleszczukE Skopińska-Skopińska
May 17, 2011·Annual Review of Nutrition·Dale E BaumanAdam L Lock
Jan 7, 2016·Annual Review of Food Science and Technology·Jun Ho KimYeonhwa Park
Oct 16, 2007·Analytica Chimica Acta·Carolina Moltó-PuigmartíM Carmen López-Sabater
Oct 17, 2007·Journal of the American Dietetic Association·Penny M Kris-Etherton Dietitians of Canada
May 13, 2015·Journal of Food Science·Jun Ho KimYeonhwa Park
May 15, 2015·Nutrition & Metabolism·Sailas BenjaminFriedrich Spener
Sep 10, 2004·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·L D WhighamR L Atkinson
Jul 28, 2006·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Lokenga Badinga, Elizabeth S Greene
Jul 15, 2015·The Cochrane Database of Systematic Reviews·Mario F Delgado-NogueraAssimina Galli-Tsinopoulou
Oct 26, 2011·International Journal of Food Sciences and Nutrition·Ana Claudia BerenhauserJane Mara Block
Apr 3, 2020·The Journal of Nutrition·Gabriela E LeghiBeverly S Muhlhausler
Dec 8, 2005·The American Journal of Clinical Nutrition·Erin E MosleyMark A McGuire
Jan 22, 2008·The Journal of Nutrition·Dale E BaumanLance H Baumgard
Feb 18, 2003·Current Opinion in Clinical Nutrition and Metabolic Care·Philip C Calder, Richard J Deckelbaum
Mar 1, 2005·The Journal of Nutrition·Nicole K AndersonMichelle K McGuire
May 26, 2004·The American Journal of Clinical Nutrition·Michael W Pariza
Jul 24, 2021·The British Journal of Nutrition·Shiksha AdhikariElske M Brouwer-Brolsma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.