Maternal welfare, morbidity and mortality 6-15 years after a pregnancy complicated by alcohol and substance abuse: a register-based case-control follow-up study of 524 women

Drug and Alcohol Dependence
Hanna KahilaErja Halmesmäki

Abstract

A register-based retrospective case-control study to investigate the long-term morbidity, mortality, and welfare among women with alcohol and/or substance misuse identified during pregnancy. Cohort of 524 women followed-up ante- and perinatally 1992-2001 at special out-patient clinics of maternity hospitals in the capital area of Finland. The control group of 1792 women with no evidence of alcohol or substance misuse was matched for maternal age, parity, date of birth and hospital of index delivery. Both groups were followed-up until end of 2007. 7.9% (42/524) of the cases and 0.2% (4/1792) of the controls had died by the end of the median follow-up of 9 years (OR 38, 95% CI 14-108). The cases displayed significant morbidity requiring in-patient care in the areas of mental disorders (AOR 8.8, 95% CI 6.5-11.9), viral (AOR 23.5, 95% CI 8.8-62.7) and bacterial (AOR 6.1, 95% CI 3.5-10.4) infections, skin diseases (AOR 3.9, 95% CI 2.0-7.8) and injury and poisoning (AOR 4.2, 95% CI 3.1-5.6). The cases displayed more out-patient visits (OR 2.7, 95% CI 2.7-2.8). Their mean length of hospital stay was longer compared to controls (10.3 vs. 4.4 days, p<0.001). The risk of pension granted due to a disorder, disease or disability (OR 8.8, 9...Continue Reading

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Citations

Aug 21, 2015·Archives of Disease in Childhood. Fetal and Neonatal Edition·Hilary DaviesArturo Gonzalez-Izquierdo
Mar 19, 2014·Child: Care, Health and Development·A Gonzalez-IzquierdoR Gilbert
Nov 20, 2014·Addiction·Kirsimarja RaitasaloPia Mäkelä
Aug 26, 2014·The International Journal on Drug Policy·Ifeoma N OnyekaJussi Kauhanen
Feb 6, 2015·Scandinavian Journal of Public Health·Sushil BasnetJussi Kauhanen
Feb 7, 2020·Maternal and Child Health Journal·Jean C HostageDebra Sepulveda
Sep 17, 2020·Nordisk alkohol- & narkotikatidskrift : NAT·Anne M KoponenHanna Kahila
Oct 2, 2020·Der Nervenarzt·Thomas HillemacherHelge Frieling

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