Mathematical model of modified hybrid pump mechanism for cardiopulmonary resuscitation.

Computer Methods and Programs in Biomedicine
Dong Ah Shin, Jung Chan Lee

Abstract

The "Cardiac pump theory" and "Thoracic pump theory" are representative theories of cardiopulmonary resuscitation (CPR) mechanisms. Based on these theories, many studies on mathematical modeling have been performed to help understand hemodynamics during CPR. However, there are parts that do not yet properly reflect the physiology of CPR. Therefore, this study aims to develop a lumped parameter model of CPR that can more accurately reflect the current CPR physiology. By adding compartments of the superior and inferior vena cava of the thoracic cavity to the existing CPR model, and the "Hybrid pump" mechanism was applied to simulate CPR. To compare the hemodynamics of the conventional CPR model and the developed CPR model, various conditions, such as active compression-decompression CPR with an impedance threshold valve device (ACD-CPR+ITV), head-up-tilt (HUT), and head-down-tilt (HDT), were simulated. The coronary perfusion pressure (CPP) was compared by modulating the compression ratio of the atrium and ventricle with the thoracic pump factor. The result for the comparison of coronary blood flow showed that the existing model is predominant in the compression phase, whereas the developed model is dominant in the relaxation phas...Continue Reading

References

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