PMID: 8939708Nov 1, 1996Paper

Matrix metalloproteinases and the development of cancer

Chemistry & Biology
L M Coussens, Z Werb

Abstract

Proteolytic remodeling of the extracellular matrix is an important aspect of the creation and progression of cancer. Matrix metalloproteinases are important at several points during multi-stage neoplastic progression in tumor cells and responding blood vessels, inflammatory cells and stroma.

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