Matrix solid-phase dispersion extraction and high-performance liquid chromatographic determination of residual sulfonamides in chicken

Journal of Chromatography. a
K Kishida, Naoto Furusawa

Abstract

Simultaneous determination of the six sulfonamides (SAs) sulfadiazine, sulfadimidine, sulfamonomethoxine, sulfamethoxazole, sulfadimethoxine and sulfaquinoxaline in chicken using matrix solid-phase dispersion (MSPD) with neutral aluminium oxide as an MSPD sorbent and high-performance liquid chromatography (HPLC) is presented. In the present MSPD, six SAs could be isolated by only one step, elution with a 70% (v/v) aqueous ethanol solution, without the sorbent conditioning and the sorbent-tissue matrix washing. For the HPLC determination, a LiChrospher 100 RP-8 and a mixture of 1% acetic acid solution (pH 3.0, in water)-acetonitrile-N,N-dimethylformamide (78:22:5, v/v/v) as the mobile phase with a photodiode array detector were used. Average recoveries were greater than 87.6% with relative standard deviations between 0.5 and 8.6%. The total time and amount of solvent required for the analysis of one sample were <1.5 h and <12 ml, respectively.

Citations

Mar 15, 2006·Analytical and Bioanalytical Chemistry·M Gratacós-CubarsíJ A García-Regueiro
Feb 8, 2008·Analytical and Bioanalytical Chemistry·M García-LópezI Rodríguez
May 21, 2011·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·C L ChitescuC Moisoiu
Nov 28, 2006·Journal of Biochemical and Biophysical Methods·Sara Bogialli, Antonio Di Corcia
Nov 17, 2006·Journal of Biochemical and Biophysical Methods·Steven A Barker
Jan 17, 2012·Biosensors & Bioelectronics·Kyung-Mi SongChangill Ban
May 24, 2014·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Mingyuan ShaoYong Yu
Feb 3, 2012·Journal of Chromatographic Science·Yupu ZhangYinghua Wang
May 14, 2016·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Min FengYunji Wei

Related Concepts

Metazoa
Calibration
High Pressure Liquid Chromatography Procedure
Statistical Sensitivity
Sulfonamides

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