Maturation and fertilization of morphologically immature human oocytes in a program of in vitro fertilization

Fertility and Sterility
L L VeeckH W Jones

Abstract

Oocytes of varying stages of maturity were aspirated from follicles primed with either human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG) or a combination of follicle-stimulating hormone (FSH), hMG and hCG. Of the aspirated oocytes from 44 cycles, 74 were considered to be immature by virtue of morphologic characteristics of the oocytes and the degree of intercellular expansion of the associated cumular and membrana granulosa cells. After incubation periods of 22 to 35 hours in a Ham's F-10-based culture medium, these immature oocytes were inseminated with sperm donated by the patient's husband. Ultimately, 44 conceptuses were transferred to the respective uteri of 30 patients. Eight pregnancies were established as a result of these 30 transfers, two of which resulted from the transfer of only developed immature oocytes.

Citations

Apr 1, 1991·Journal of in Vitro Fertilization and Embryo Transfer : IVF·H C Liu, Z Rosenwaks
Oct 1, 1991·Journal of in Vitro Fertilization and Embryo Transfer : IVF·D DickerT Levy
Jan 1, 1988·Annals of the New York Academy of Sciences·A PellicerA H De Cherney
Jan 1, 1988·Archives of Gynecology and Obstetrics·W FeichtingerJ Hoyer
Apr 1, 1987·Journal of in Vitro Fertilization and Embryo Transfer : IVF·S S EntmanA C Wentz
Jan 1, 1985·Annals of the New York Academy of Sciences·L L Veeck
Dec 1, 1985·Journal of in Vitro Fertilization and Embryo Transfer : IVF·T PexiederP Janecek
Dec 15, 1985·Experientia·R J van KooijA Campana
Mar 1, 1985·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J V Van der MerweP Hurter
Sep 1, 1984·Journal of in Vitro Fertilization and Embryo Transfer : IVF·R A BronsonG W Cooper
Nov 1, 1993·Journal of Assisted Reproduction and Genetics·M R FlukerS Daya
May 7, 2004·Current Opinion in Obstetrics & Gynecology·Ri-Cheng ChianSeang-Lin Tan
Jan 26, 2006·Endocrine Reviews·Nick S MacklonBart C J M Fauser
Apr 6, 2006·Reproductive Biology and Endocrinology : RB&E·Hang YinRoger G Gosden
Mar 19, 2008·Human Reproduction·Gayle M JonesAlan O Trounson
Nov 5, 2010·Clinical Obstetrics and Gynecology·Baris AtaSeang Lin Tan
Dec 1, 1992·Journal of Assisted Reproduction and Genetics·B Van WissenO Bomsel-Helmreich
Oct 1, 1990·Journal of in Vitro Fertilization and Embryo Transfer : IVF·M C EdelsteinS J Muasher
Dec 1, 1986·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J F Van UemZ Rosenwaks
Oct 1, 1988·Journal of in Vitro Fertilization and Embryo Transfer : IVF·B D CowanV Lockard
Jun 1, 1985·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J A RockN B Rosenshein
Jun 1, 1987·Journal of in Vitro Fertilization and Embryo Transfer : IVF·S LenzK Petersen
Feb 1, 1993·Journal of Assisted Reproduction and Genetics·A EbrahimJ P Van der Merwe
Aug 1, 1995·Journal of Assisted Reproduction and Genetics·T J Gelety, R P Buyalos
Sep 1, 1995·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·P InaudiP De Grandi
Nov 5, 2004·Médecine sciences : M/S·Jacques Testart
Jun 6, 2013·Journal of Assisted Reproduction and Genetics·Duo WeiPeng Wang
Oct 12, 2013·Molecular Human Reproduction·Stephen G Hillier
Oct 1, 1992·Journal of Assisted Reproduction and Genetics·J SantalóA M Estop
Oct 1, 1989·Journal of in Vitro Fertilization and Embryo Transfer : IVF·G E HofmannG S Jones
Dec 1, 1985·Journal of in Vitro Fertilization and Embryo Transfer : IVF·B CacciatoreP Ylöstalo
Jan 1, 1985·Annals of the New York Academy of Sciences·E RudakB Goldman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.