Maturation and interhemispheric asymmetry in neurite density and orientation dispersion in early childhood.

NeuroImage
Dennis DimondSigne Bray

Abstract

The brain's white matter undergoes profound changes during early childhood, which are believed to underlie the rapid development of cognitive and behavioral skills during this period. Neurite density, and complexity of axonal projections, have been shown to change across the life span, though changes during early childhood are poorly characterized. Here, we utilize neurite orientation dispersion and density imaging (NODDI) to investigate maturational changes in tract-wise neurite density index (NDI) and orientation dispersion index (ODI) during early childhood. Additionally, we assess hemispheric asymmetry of tract-wise NDI and ODI values, and longitudinal changes. Two sets of diffusion weighted images with different diffusion-weighting were collected from 125 typically developing children scanned at baseline (N = 125; age range = 4.14-7.29; F/M = 73/52), 6-month (N = 8; F/M = 8/0), and 12-month (N = 52; F/M = 39/13) timepoints. NODDI and template-based tractography using constrained spherical deconvolution were utilized to calculate NDI and ODI values for major white matter tracts. Mixed-effects models controlling for sex, handedness, and in-scanner head motion were utilized to assess developmental changes in tract-wise NDI an...Continue Reading

References

Sep 24, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Elizabeth R SowellArthur W Toga
Mar 18, 2006·Neuroimaging Clinics of North America·Pratik Mukherjee, Robert C McKinstry
Apr 17, 2008·Behavioural Neurology·G FerrettiD Brizzolara
Jun 20, 2008·Cerebral Cortex·J DuboisG Dehaene-Lambertz
Jul 4, 2008·Neuroreport·Lucia van EimerenDaniel Ansari
Oct 5, 2010·NMR in Biomedicine·Mariana Lazar
Feb 15, 2011·NeuroImage·David RaffeltOlivier Salvado
Jun 28, 2011·NeuroImage·Els FieremansJoseph A Helpern
Jul 29, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Catherine Lebel, Christian Beaulieu
Sep 24, 2011·Neuropsychologia·Christian K TamnesKristine B Walhovd
Oct 8, 2011·NeuroImage·Mark JenkinsonStephen M Smith
Apr 10, 2012·PloS One·René M H BesselingWalter H Backes
Jun 20, 2012·Developmental Science·Stephanie Burnett HeyesMasud Husain
Dec 15, 2012·NeuroImage·Robert E SmithAlan Connelly
Jan 5, 2013·Pediatric Radiology·Shoko YoshidaSusumu Mori
Mar 19, 2013·NeuroImage·Nagulan RatnarajahAnqi Qiu
Aug 2, 2013·The British Journal of Developmental Psychology·Kate BreckenridgeJanette Atkinson
Mar 8, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Eva Alonso-OrtizG Bruce Pike
Apr 9, 2014·Brain Structure & Function·Douglas C DeanSean C L Deoni
May 9, 2014·Cerebral Cortex·Jae W SongEmi Takahashi
Aug 15, 2014·Cerebral Cortex·Rasmus Krarup SigaardBente Pakkenberg
Sep 16, 2014·NeuroImage·Tim B DyrbyHartwig R Siebner
Nov 22, 2014·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Jennifer C MullaneElizabeth N McLaughlin
Oct 16, 2015·NeuroImage·Simon DucharmeUNKNOWN Brain Development Cooperative Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.