Maximal Points of Head's Zone in Fixed Drug Eruption.

Annals of Dermatology
Sang Sin LeeJeung Hoon Lee

Abstract

The principles determining the primary localization of lesions in fixed drug eruption (FDE) are still unknown. Studies investigating the predilection areas in FDE have indicated drug-related, trauma-related, or inflammation-related specific site involvement, as well as visceracutaneous reflex-related specific site involvement. The importance of viscerocutaneous reflexes for the location of dermatoses was first recognized in the 1960s. Head's zones are viscerocutaneous reflex projection fields on the skin that extend over certain dermatomes and possess a reflex-associated maximal point. Recently, in a Turkish collective of patients, three women with the primary location of FDE lesions on the maximal points of Head's zones were presented. We also experienced 3 cases with FDE where the lesions were located at specific sites (buttocks), the so-called maximal points of Head's zones, which are known to be the most active dermatomal areas of an underlying visceral pathology. An underlying internal disturbance (ureter stone, pyelonephritis and chronic pelvic inflammatory disease) was found in all 3 patients, corresponding to the organ-related maximal point of Head's zones in each case. In conclusion, the primary location of FDE lesions...Continue Reading

References

Dec 1, 1991·International Journal of Dermatology·T P Thankappan, J Zachariah
Nov 1, 1988·Pediatric Dermatology·A J KanwarR Sharma
Aug 1, 1996·The Journal of Dermatology·V K SharmaA N Gill
Mar 25, 1999·Clinics in Dermatology·G Stüttgen
Jul 20, 2002·Current Opinion in Allergy and Clinical Immunology·Tetsuo ShioharaYuichi Teraki
Sep 10, 2002·Dermatology : International Journal for Clinical and Investigative Dermatology·Yoshiko Mizukawa, Tetsuo Shiohara
Sep 19, 2003·The Journal of Allergy and Clinical Immunology·Yuichi Teraki, Tetsuo Shiohara
Jul 13, 1962·Deutsche medizinische Wochenschrift·W KOSENOW, R A PFEIFFER
Nov 26, 2003·Journal of the American Academy of Dermatology·Esen Ozkaya-Bayazit
May 17, 2005·Autoimmunity Reviews·Tetsuo Shiohara, Yoshiko Mizukawa
Aug 17, 2006·International Journal of Dermatology·Virendra N Sehgal, Govind Srivastava

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