Maximizing the power of comparing single cases against a control sample: an argument, a program for making comparisons, and a worked example from the Pyramids and Palm Trees Test

Cognitive Neuropsychology
Johan Hulleman, Glyn W Humphreys

Abstract

In neuropsychological research, it is frequently necessary to compare the performance of a single case with that of a control sample. Recently, there has been a discussion about whether existing methods are adequate in preventing Type 1 errors due to increased variability in the single-case data (Crawford, Garthwaite, Howell, & Gray, 2004; Mitchell, Mycroft, & Kay, 2004; Mycroft, Mitchell, & Kay, 2002) and about the power of any comparisons. In this paper, we propose an extension of the modified t test introduced by Crawford and Howell (1998). We provide Monte Carlo simulations that show that it is possible to increase the power of the modified t test by retesting the single case. We also make available a computer program that implements the method introduced in this paper and that can be used by neuropsychologists to test for a difference between a single case and a control group. We apply our procedure to an example of a patient examined on the "Pyramids and Palm Trees" test.

References

Jul 28, 2005·Neuropsychologia·John R CrawfordKeith R Laws
May 1, 2003·Cognitive Neuropsychology·Glyn W Humphreys, M Jane Riddoch

❮ Previous
Next ❯

Citations

Mar 15, 2008·Cognitive Neuropsychology·M Jane RiddochGlyn W Humphreys
Aug 26, 2011·Cognitive Neuropsychology·Rebecca M Scott, Carolyn E Wilshire
Sep 21, 2013·Journal of Cognitive Neuroscience·Vaia LestouGlyn W Humphreys
Feb 12, 2014·Cognitive Neuropsychology·Paula Speer, Carolyn E Wilshire
Mar 13, 2021·Current Opinion in Behavioral Sciences·Carolina Deifelt Streese, Daniel Tranel

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.