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Mbd3 and deterministic reprogramming

bioRxiv

Jan 16, 2015

Paul BertoneJosé C.R. Silva

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Abstract

Rais et al. (Nature 502: 65-70) reported that suppressing formation of the Nucleosome Remodelling and Deacetylase (NuRD) complex by depleting its structural component Mbd3 promotes near 100% induction of somatic cells reprogrammed to pluripotency. These results have not been independent...read more

Mentioned in this Paper

Embryo
Embryonic Development
Enhancer Elements, Genetic
Genome
Nucleosomes
Stem Cells
Genomics
Mi-2 Nucleosome Remodeling and Deacetylase Complex
Nucleosome Location
Diploid Cell
21
16
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  • Mbd3 and deterministic reprogramming

    bioRxiv

    Jan 16, 2015

    Paul BertoneJosé C.R. Silva

    PMID: 990013904

    DOI: 10.1101/013904

    Abstract

    Rais et al. (Nature 502: 65-70) reported that suppressing formation of the Nucleosome Remodelling and Deacetylase (NuRD) complex by depleting its structural component Mbd3 promotes near 100% induction of somatic cells reprogrammed to pluripotency. These results have not been independent...read more

    Mentioned in this Paper

    Embryo
    Embryonic Development
    Enhancer Elements, Genetic
    Genome
    Nucleosomes
    21
    16

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