Jan 16, 2015

Mbd3 and deterministic reprogramming

BioRxiv : the Preprint Server for Biology
Paul BertoneJosé C.R. Silva

Abstract

Embryonic development requires the activity of the Nucleosome Remodeling and Deacetylase (NuRD) complex. NuRD functionality can be ablated by rendering cells devoid of methyl-CpG-binding domain protein 3 (Mbd3), a critical component that confers stability to the complex[1][1]. Previous studies noted

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Mentioned in this Paper

Embryo
Study
Nucleosomes
Genome
MBD3 gene
Mi-2 Nucleosome Remodeling and Deacetylase Complex
Embryonic Development
Nucleosome Location
POU5F1
Genomics

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