MBT-ASTRA: A suitable tool for fast antibiotic susceptibility testing?

Methods : a Companion to Methods in Enzymology
Katrin SparbierM Kostrzewa

Abstract

The increasing resistance to antibiotics is an urgent health care problem. Detection of resistant microorganisms is the pre-requisite for initiating an adequate therapy and implementing respective hygiene measures. Depending on the species and the method employed for analysis, the time to result of antibiotic resistance testing ranges between five and 24h. As MALDI-TOF MS has become an established tool for the fast species identification in microbiological laboratories a time gap between the results of species identification and the information about antibiotic susceptibility arises. Here, we present a semi-quantitative MALDI-TOF MS-based approach for the detection of resistance in different species against different antibiotics.

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Citations

Jun 22, 2016·Methods : a Companion to Methods in Enzymology·Rainer Cramer
Sep 7, 2016·Expert Review of Proteomics·Maurizio Sanguinetti, Brunella Posteraro
Jun 18, 2016·Proteomics. Clinical Applications·Yannick Charretier, Jacques Schrenzel
Apr 6, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M Sanguinetti, B Posteraro
Oct 12, 2018·PloS One·Marlène SaugetDidier Hocquet
Mar 20, 2019·Nature Reviews. Genetics·Manish BoolchandaniGautam Dantas
Jul 18, 2019·Expert Review of Proteomics·Martin WelkerDavid Pincus
Apr 10, 2020·PLoS Pathogens·R Christopher D FurnissGerald Larrouy-Maumus
Jul 10, 2020·Lab on a Chip·Rathina Kumar ShanmugakaniSaurabh Mehta
Aug 8, 2020·Frontiers in Cellular and Infection Microbiology·Antti VasalaOlli H Laitinen
Feb 8, 2018·Expert Review of Proteomics·Markus Kostrzewa
Sep 19, 2018·Journal of Fungi·Maurizio Sanguinetti, Brunella Posteraro
Feb 23, 2019·Frontiers in Cellular and Infection Microbiology·Margot DelavyAlix T Coste
Jan 31, 2019·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Belén Rodríguez-SánchezGilbert Greub
Feb 15, 2020·Nature Reviews. Microbiology·Alex van BelkumWilliam Michael Dunne
Jan 27, 2019·Deutsches Ärzteblatt International·Evgeny A IdelevichKarsten Becker
Dec 3, 2020·Frontiers in Cellular and Infection Microbiology·Walter FlorioAntonella Lupetti
Oct 27, 2021·Analytical Chemistry·Christian BlumenscheitJoerg Doellinger
Jun 17, 2021·Journal of Clinical Microbiology·Evgeny A Idelevich, Karsten Becker

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