McGill Thyroid Nodule Score in Differentiating Thyroid Nodules in Total Thyroidectomy Cases of Indeterminate Nodules.

Indian Journal of Surgical Oncology
Hadi Al-HakamiMohammed A Al Garni

Abstract

Fine-needle aspiration biopsy (FNAB) is the first-line modality in the evaluation of thyroid nodules. However, the results of indeterminate pathology place the thyroid surgeon in difficult management situations. This study evaluates McGill Thyroid Nodule Score (MTNS) to identify thyroid nodules that harbor malignancy in cases of indeterminate FNABs and to guide surgeon about the need and extent of surgery. We conducted a retrospective chart review of 344 patients who underwent total thyroidectomy between January 2013 and January 2018. Patients with FNAB of indeterminate nodules (Bethesda types III, IV, and V) and calculated MTNS were included in the study. Postoperative histopathology was divided into benign and malignant groups. The median and the mean MTNS, the malignancy rate, and the standard deviations were calculated for each subgroup. Of the 344 patient charts reviewed, 106 (30.8%) had an indeterminate FNA biopsy. Eighty-one (76.4%) patients were females and 25 (23.6%) were males. Final pathology revealed malignancy in 69 patients (65.1%). The mean MTNS of patients with malignant pathology (12.81  ± 3.55) was higher than the mean in the benign group (8.32  ± 2.32). 82.4% of thyroid nodules with median MTNS of less than 8...Continue Reading

References

Oct 22, 2004·The New England Journal of Medicine·Laszlo Hegedüs
Oct 23, 2009·American Journal of Clinical Pathology·Edmund S CibasUNKNOWN NCI Thyroid FNA State of the Science Conference
Aug 26, 2011·The Journal of Clinical Endocrinology and Metabolism·Henry LiPaul W Ladenson
Apr 27, 2012·The Journal of Clinical Endocrinology and Metabolism·Martina RossiMaria Chiara Zatelli
Jun 27, 2012·The New England Journal of Medicine·Erik K AlexanderBryan R Haugen
Aug 1, 2012·Acta Cytologica·Massimo BongiovanniZubair W Baloch
Apr 13, 2013·International Journal of Health Sciences·Shagufta Tahir Mufti, Rihab Molah
Jun 13, 2013·Hematology/oncology and Stem Cell Therapy·Fazal HussainNaeem Chaudhri
Jan 9, 2016·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Feb 27, 2016·Endocrine-related Cancer·Yushan Mao, Mingzhao Xing
May 5, 2016·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Sarah KhalifeRichard J Payne
Oct 5, 2017·Cancer Control : Journal of the Moffitt Cancer Center·Pablo Valderrabano, Bryan McIver
Nov 2, 2017·Thyroid : Official Journal of the American Thyroid Association·Edmund S Cibas, Syed Z Ali
Feb 23, 2019·Saudi Journal of Medicine & Medical Sciences·Hawazen A ZarifMohamed B Satti

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