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MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

Journal of Neuroinflammation

Oct 30, 2019

Javier H JaraPembe Hande Ozdinler

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Abstract

The involvement of non-neuronal cells and the cells of innate immunity has been attributed to the initiation and progression of ALS. TDP-43 pathology is observed in a broad spectrum of ALS cases and is one of the most commonly shared pathologies. The potential involvement of the neuroim...read more

Mentioned in this Paper

Amyotrophic Lateral Sclerosis
Astrocytes
Inflammation
Laboratory mice
Electron Microscopy
Monocytes
Motor Neurons
Nerve Degeneration
Neuroglia
Neuroimmunomodulation
11
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MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

Journal of Neuroinflammation

Oct 30, 2019

Javier H JaraPembe Hande Ozdinler

PMID: 31666087

DOI: 10.1186/s12974-019-1589-y

Abstract

The involvement of non-neuronal cells and the cells of innate immunity has been attributed to the initiation and progression of ALS. TDP-43 pathology is observed in a broad spectrum of ALS cases and is one of the most commonly shared pathologies. The potential involvement of the neuroim...read more

Mentioned in this Paper

Amyotrophic Lateral Sclerosis
Astrocytes
Inflammation
Laboratory mice
Electron Microscopy
11
1

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