Mean and variability of annual haemoglobin A1c are associated with high-risk peripheral artery disease.

Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease
I-Te Lee

Abstract

Glucose variability is predictive of cardiovascular events and all-cause mortality. However, the association between peripheral artery disease and glucose variability has not been thoroughly investigated. Therefore, the standard deviation of annual haemoglobin A1c was assessed in patients with type 2 diabetes for evaluating the different risks of peripheral artery disease. A total of 4144 patients underwent an evaluation for the ankle-brachial index and the percentage of mean arterial pressure at the ankle. The first haemoglobin A1c record was retrospectively collected from each year until the ankle-brachial index measurement. The standard deviation of annual haemoglobin A1c was higher in patients with ankle-brachial index ⩽0.90 than in those with ankle-brachial index >0.90 (1.1 ± 0.9% vs 1.0 ± 0.8%, p = 0.009) and was higher in patients with percentage of mean arterial pressure ⩾45% than in those with percentage of mean arterial pressure <45% (1.1 ± 0.8% vs 1.0 ± 0.8%, p = 0.007). A high standard deviation and mean of annual haemoglobin A1c are associated with high-risk peripheral artery disease, which is defined as a combination of ankle-brachial index ⩽0.90, percentage of mean arterial pressure ⩾45% or both (odds ratio = 1.3...Continue Reading

References

May 24, 2001·The New England Journal of Medicine·W R Hiatt
Feb 13, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·R J TappUNKNOWN AusDiab Study Group
Jun 20, 2006·European Heart Journal·Curt DiehmHans Joachim Trampisch
Apr 7, 2010·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·S TavintharanTien Y Wong
May 26, 2012·Journal of Diabetes and Its Complications·Wen-Ya MaChing-Chieh Su
Nov 10, 2013·Annals of Vascular Surgery·Benjamin A EslahpazirVikram S Kashyap
Mar 22, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Lesley A InkerHarold I Feldman
Apr 8, 2014·Journal of Diabetes and Its Complications·Toshiko TakaoShoji Kawazu
Feb 26, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Tomoko HashimotoKimihiko Kichikawa
May 28, 2016·Asian Cardiovascular & Thoracic Annals·Takuro ShirasuToshiaki Watanabe
Aug 10, 2016·Journal of Diabetes and Its Complications·Neda LaiteerapongElbert S Huang
Nov 18, 2016·Nature Reviews. Cardiology·F Gerry R FowkesMichael H Criqui
Apr 6, 2017·The New England Journal of Medicine·Sripal BangaloreDavid D Waters
Oct 17, 2017·Diabetes & Metabolism·Chia-Lin LeeYu-Fen Li
Nov 8, 2017·Expert Review of Endocrinology & Metabolism·Ian Charles DavisStephen N Davis
Dec 16, 2017·Journal of Diabetes and Its Complications·Victor W ZhongElizabeth J Mayer-Davis
Mar 28, 2018·Diabetes, Obesity & Metabolism·Emanuela OrsiUNKNOWN Renal Insufficiency and Cardiovascular Events (RIACE) Study Group
Dec 12, 2018·Heart, Lung & Circulation·Jinggang Xia, Chunlin Yin
Dec 19, 2018·Diabetes Care·UNKNOWN American Diabetes Association
Feb 16, 2019·British Journal of Pharmacology·Jennifer J DuPontIris Z Jaffe

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