Measles: a disease often forgotten but not gone

Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi
A Kc LeungC M Sergi

Abstract

Measles (rubeola) is a highly contagious vaccine-preventable disease caused by the measles virus-a virus of the Paramyxoviridae family. The illness typically begins with fever, runny nose, cough, and pathognomonic enanthem (Koplik spots) followed by a characteristic erythematous, maculopapular rash. The rash classically begins on the face and becomes more confluent as it spreads cephalocaudally. Laboratory confirmation of measles virus infection can be based on a positive serological test for measles-specific immunoglobulin M antibody, a four-fold or greater increase in measles-specific immunoglobulin G between acute and convalescent sera, isolation of measles virus in culture, or detection of measles virus ribonucleic acid by reverse transcriptase-polymerase chain reaction. Complications occur in 10% to 40% of patients, and treatment is mainly symptomatic. Bacterial superinfections, if present, should be properly treated with antibiotics. To eradicate measles, universal childhood immunisation and vaccination of all susceptible individuals with measles vaccine would be ideal. In developed countries, routine immunisation with measles-containing vaccine is recommended, with the first and second doses at ages 12 to 15 months and 4...Continue Reading

Citations

Sep 15, 2020·Curēus·Abba Musa AbdullahiRomil Singh
Dec 15, 2020·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Qingjie FanMing Li
Dec 3, 2020·Curēus·Abba Musa AbdullahiNusrat Jahan
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rambod AbiriSonia Malik
Feb 6, 2020·Recent Patents on Inflammation & Allergy Drug Discovery·Ronald C M FungAlexander K C Leung

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