Measurement of 5-methyltetrahydrofolic acid in man by high-performance liquid chromatography

Metabolism: Clinical and Experimental
R J LeemingC G Hamon

Abstract

5-Methyl-5,6,7,8-tetrahydrofolic (5-methylTHF) acid can be measured in human serum and whole blood by fluorescence after deproteinization with perchloric acid and separation by high-performance liquid chromatography (HPLC). The technique is sensitive, rapid, and correlates with existing methods for total folates.

References

Jan 1, 1985·Journal of Inherited Metabolic Disease·I SmithB Kendall
May 1, 1962·The Journal of Clinical Investigation·V HERBERTJ M BUCHANAN

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Citations

May 11, 2006·Analytical and Bioanalytical Chemistry·A Muñoz de la PeñaA Jiménez Girón
Jul 1, 1995·Journal of Pharmaceutical and Biomedical Analysis·C Cruces BlancoM Román Ceba
Mar 31, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·J Rodríguez FloresM J Rodríguez Gómez
Oct 26, 2012·Journal of Chromatographic Science·Samy EmaraRamzia Ei-Bagary
Oct 29, 2003·Journal of Pediatric Gastroenterology and Nutrition·Emi NakanoHilary J Powers
Sep 20, 2012·Biomedical Chromatography : BMC·Elisabeth OdinBengt Gustavsson
May 18, 1999·Molecular Genetics and Metabolism·M D LucockM I Levene
Jul 14, 2001·Arteriosclerosis, Thrombosis, and Vascular Biology·S N DoshiJ Goodfellow
Sep 20, 2018·Journal of Clinical Pathology·Agata Sobczyńska-Malefora, Dominic J Harrington
Mar 13, 2017·Toxicology Research·Marília BaierleSolange Cristina Garcia

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