PMID: 697311Jul 1, 1978Paper

Measurement of acetate in aqueous solutions and plasma by gas phase chromatography using a porous polymer stationary phase

Annals of Clinical Biochemistry
M F Laker, M A Mansell

Abstract

A method of acetate determination by gas phase chromatography using a porous polymer stationary phase is reported that is suitable for use with aqueous and plasma samples. It is linear up to 100 mmol/l and has a coefficient of variation of less than 4% for acetate values of greater than 1 mmol/l. The recovery of acetate from plasma is 92% and sample retention time is 3 minutes. The reference range of plasma acetate in a group of 40 apparently healthy subjects was from less than 0.1 to 0.35 mmol/l. The frequently encountered problem of absorption and ghosting of volatile fatty acids is overcome without the addition of formic acid vapour to the carrier gas.

References

Apr 15, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·G Desch, B Descomps
Jan 1, 1975·Methods in Enzymology·M Wadke, J M Lowenstein
May 30, 1973·Clinica Chimica Acta; International Journal of Clinical Chemistry·O StokkeR Schnitler
Jun 1, 1969·Clinica Chimica Acta; International Journal of Clinical Chemistry·J B Whitefield
May 1, 1962·The Journal of Clinical Investigation·F LUNDQUISTS MUNCK-PETERSEN
Feb 10, 1962·Nature·F LUNDQUIST

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Citations

Jul 30, 1983·British Medical Journal·M A Mansell, A J Wing
Jun 1, 1979·British Journal of Haematology·M Mansell, A J Grimes

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