PMID: 2122372Sep 1, 1990Paper

Measurement of human nasal ciliary motility using computerized microphotometry

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
P P PhillipsE B Kern

Abstract

A new computerized technique for the assessment of human nasal ciliary beat frequency is described. Thirty normal volunteers underwent nasal cytologic brushing to obtain ciliary samples. In each subject, 150 ciliary beats were analyzed from each of 50 separate ciliated cell clusters. The ciliary beat frequency for each area was determined with fast Fourier transformation. The results were plotted on a histogram to determine the ciliary beat distribution. The mean frequency for these samples was 11.29 Hz, with a standard deviation of 0.96 Hz. The median frequency for these samples was 11.25 Hz. These results show a marked improvement over hand-counting microphotometry techniques because of the much larger sampling size and elimination of much human error. We believe this method of ciliary analysis represents a significant advancement in the evaluation of ciliary function and should assist in the diagnosis of patients with congenital and acquired forms of ciliary dysmotility.

References

Apr 1, 1988·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·J L FergusonW J Martin
Jul 1, 1985·International Journal of Pediatric Otorhinolaryngology·D Passàli, M Bianchini Ciampoli
Mar 1, 1981·Acta Oto-laryngologica·E PuchelleA Bertrand
Jan 1, 1982·Clinical Science·E PuchelleA Bertrand

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Citations

Apr 16, 2005·The Journal of Pharmacy and Pharmacology·Svetlana DimovaPatrick Augustijns
Jan 1, 1995·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·M Jorissen, A Bessems
Apr 15, 2008·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Luo ZhangZhongyan Liu
Dec 1, 1991·The Laryngoscope·S K SteinsvågJ Olofsson
Jul 1, 1994·The Annals of Otology, Rhinology, and Laryngology·S Lindberg, T Runer
Feb 3, 2000·Clinical Nuclear Medicine·D Di GiudaG De Rossi
Sep 1, 1996·The Annals of Otology, Rhinology, and Laryngology·S LindbergL Thomasson
Jun 1, 1995·The Journal of Experimental Zoology·G Di CarlantonioP Talbot
Dec 8, 2004·Toxicology in Vitro : an International Journal Published in Association with BIBRA·S DimovaP Augustijns
Feb 24, 2005·International Journal of Pharmaceutics·S DimovaP Augustijns

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