PMID: 48898Jun 7, 1975Paper

Measurement of liver-cadmium concentrations in patients and industrial workers by neutron-activation analysis

Lancet
T C HarveyJ H Fremlin

Abstract

A new, rapid, non-invasive technique for measuring tissue-cadmium concentrations in patients and industrial workers has been designed and developed with a view to studying the cadmium content of the liver. The method utilises the principle of neutron-activation analysis whereby the specific changes produced by the inter action of nuclei and neutrons are analysed. Liver-cadmium content has been studied in cadavers and in four men with known of suspected cadmium poisoning. The patients all showed very high liver-cadmium levels of between 35 and 200 p.p.m. compared with under 1.0 p.p.m. in non-exposed subjects. The dose of radiation used in clinical studies was 0.4-1.0 rem and the detection limit of cadmium was 1.0 p.p.m.

References

Jan 1, 1975·Physics in Medicine and Biology·J S McLellanT C Harvey
Apr 1, 1974·Lancet·A Ulander, O Axelson
Jul 5, 1969·Lancet·H Holden
Apr 12, 1972·Nature: New Biology·H C BigginM J Chamberlain
Dec 1, 1972·Journal of Chronic Diseases·G P LewisL L Coughlin
Jun 4, 1971·Nature·G T Goodman, T M Roberts
Apr 1, 1971·Environmental Research·D F FlickJ M Dimitroff
Mar 1, 1970·The International Journal of Applied Radiation and Isotopes·S H CohnR G Fairchild
Oct 1, 1970·Clinica Chimica Acta; International Journal of Clinical Chemistry·A S Curry, A R Knott
Mar 1, 1967·Circulation·H A Schroeder

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Citations

Apr 1, 1980·The Science of the Total Environment·K Nomiyama
Dec 18, 1976·Lancet·J S Burke, J J Butler
Mar 10, 1979·Lancet·T C HarveyS P Downey
Mar 26, 1988·Lancet·A G DavisonM C Scott
May 1, 1977·British Journal of Industrial Medicine·G S FellF E Hussein
Aug 1, 1980·British Journal of Industrial Medicine·J D BlaineyT C Harvey
Jun 1, 1997·Occupational and Environmental Medicine·J BörjessonS Mattsson
Jan 1, 1981·Physics in Medicine and Biology·L Ahlgren, S Mattsson
Mar 1, 1979·Physics in Medicine and Biology·B J ThomasJ H Fremlin
Jul 1, 1981·Physics in Medicine and Biology·W D MorganS H Cohn

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