PMID: 8594009Nov 1, 1995Paper

Measurement of lung expansion with computed tomography and comparison with quantitative histology

Journal of Applied Physiology
H O CoxsonJ C Hogg

Abstract

The total and regional lung volumes were estimated from computed tomography (CT), and the pleural pressure gradient was determined by using the milliliters of gas per gram of tissue estimated from the X-ray attenuation values and the pressure-volume curve of the lung. The data show that CT accurately estimated the volume of the resected lobe but overestimated its weight by 24 +/- 19%. The volume of gas per gram of tissue was less in the gravity-dependent regions due to a pleural pressure gradient of 0.24 +/- 0.08 cmH2O/cm of descent in the thorax. The proportion of tissue to air obtained with CT was similar to that obtained by quantitative histology. We conclude that the CT scan can be used to estimate total and regional lung volumes and that measurements of the proportions of tissue and air within the thorax by CT can be used in conjunction with quantitative histology to evaluate lung structure.

Citations

Jul 17, 2004·American Journal of Respiratory and Critical Care Medicine·Harvey O CoxsonC Laird Birmingham
Nov 2, 2004·American Journal of Respiratory and Critical Care Medicine·Yasutaka NakanoPeter D Paré
Dec 2, 2006·Journal of Applied Physiology·Priya RavikumarConnie C W Hsia
Apr 21, 2011·Journal of the American College of Nutrition·Rui JiangR Graham Barr
May 19, 2012·Journal of Applied Physiology·Peter D ParéHarvey O Coxson
Mar 22, 2014·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Firas S AhmedR Graham Barr
Jul 2, 2014·Annals of the American Thoracic Society·Eric A HoffmanR Graham Barr
Oct 13, 2016·Journal of Magnetic Resonance Imaging : JMRI·Khadija SheikhUNKNOWN Canadian Respiratory Research Network
Dec 26, 2001·American Journal of Respiratory Cell and Molecular Biology·Bernard MeshiJames C Hogg
Feb 13, 2001·Physiological Genomics·W MitznerW Lee
May 19, 2000·The British Journal of Radiology·S E Connor, J F Olliff
Jun 12, 2010·Journal of Applied Physiology·Stephen ChoyGrace Parraga
Jan 16, 2007·European Journal of Applied Physiology·M J MacNuttD C McKenzie
Apr 3, 2012·European Radiology·Matthew S BrownJonathan G Goldin
Mar 2, 1999·American Journal of Respiratory and Critical Care Medicine·H O CoxsonJ C Hogg
Jul 30, 2005·American Journal of Respiratory and Critical Care Medicine·Tanya M MartínezRobert S Tepper
May 29, 1998·American Journal of Respiratory and Critical Care Medicine·M D BeckerM E Ginsburg
Oct 16, 2004·Investigative Radiology·Berend C Stoel, Jan Stolk
Dec 26, 2001·American Journal of Respiratory and Critical Care Medicine·P A Gevenois, M Estenne
Jun 23, 2004·Journal of Applied Physiology·Priya RavikumarConnie C W Hsia
Aug 11, 2006·Pediatric Radiology·Pim A de JongYasutaka Nakano
Jan 4, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Isabel DregelyKai Ruppert
Aug 17, 2017·Annals of the American Thoracic Society·Sandeep BodduluriSurya P Bhatt
Apr 17, 2020·Journal of Applied Physiology·Dragoş M VasilescuJames C Hogg
Jun 16, 2007·Journal of Applied Physiology·Jordan A GuenetteDonald C McKenzie
Aug 1, 2009·Der Radiologe·A W Reske, M Seiwerts
Mar 29, 2002·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Ki Nam LeeW Richard Webb
Feb 24, 2009·AJR. American Journal of Roentgenology·Klaus Loureiro IrionPaulo Oliveira Irion
Dec 4, 2014·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yu-Sen HuangYeun-Chung Chang
Feb 23, 2019·American Journal of Respiratory and Critical Care Medicine·Dragoş M VasilescuMeiLan K Han
Feb 5, 2010·American Journal of Respiratory and Critical Care Medicine·Connie C W HsiaUNKNOWN ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure
Jan 16, 2013·Critical Care Medicine·Andreas W ReskeMarcelo B P Amato

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.