PMID: 9647442Jul 1, 1998Paper

Measurement of myocardial infarct size by electron beam computed tomography: a comparison with 99mTc sestamibi

Investigative Radiology
A SchmermundJohn A Rumberger

Abstract

The authors sought to determine, using a variety of regional left ventricular ejection fraction (EF) and wall thickening (WTh) criteria, the applicability to measure left ventricular (LV) infarct size using electron-beam CT (EBCT) in patients as compared with technetium 99m (99mTc) sestamibi scanning as reference standard. Twelve patients (age 57 +/- 11 years) underwent 99mTc sestamibi scanning and EBCT at hospital discharge after an acute index anterior myocardial infarction. Left ventricular infarct size was defined using standard 99mTc sestamibi scanning. Regional EF and WTh were analyzed on each EBCT scan with use of a floating epicardial centroid method. In five contiguous LV tomograms, the amount of infarcted myocardium was estimated using the following EF and WTh criteria: EF < or = 35%, 30%, 25%, 20%, and WTh < or = 2 mm, 1 mm, and 0 mm. Infarct size measured with 99mTc sestamibi was 33.3% (+/- 18.3%) (mean +/- SD, range 6%-54%) of the LV. Using an EF < or = 35% or absolute WTh < or = 2 mm as criteria for infarcted myocardium, EBCT yielded 28% (+/- 17%) and 27% (+/- 16%), respectively (P = NS, paired Student's t test, versus 99mTc sestamibi). Although, with use of the other criteria, EBCT tended to underestimate infarct...Continue Reading

References

May 1, 1991·Journal of the American College of Cardiology·T F ChristianB J Gersh
Oct 1, 1991·Journal of the American College of Cardiology·E RoigB H Brundage
Sep 1, 1986·Journal of the American College of Cardiology·P LanzerC B Higgins
Mar 1, 1995·Journal of the American College of Cardiology·P ChareonthaitaweeJ A Rumberger

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Citations

Jan 9, 2007·European Radiology·Gabriele A KrombachAndreas H Mahnken
May 24, 2008·The International Journal of Cardiovascular Imaging·Andreas Horst MahnkenMichael Scheuering
Feb 22, 2012·Insights Into Imaging·Konstantin NikolaouBernd J Wintersperger
Jul 25, 2006·The American Journal of Cardiology·Koen NiemanThomas J Brady
Dec 10, 1999·Investigative Radiology·V M Runge
Apr 20, 2004·Journal of Computer Assisted Tomography·Konstantin NikolaouChristoph R Becker

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