PMID: 8440411Feb 1, 1993Paper

Measurement of nitric oxide in biological models

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
S Archer

Abstract

Nitric oxide (NO) is a small, gaseous, paramagnetic radical with a high affinity for interaction with ferrous hemoproteins such as soluble guanylate cyclase and hemoglobin. Interest in NO measurement increased exponentially with the discovery that NO or a related compound is the endothelium-derived relaxing factor (EDRF). In addition to being a potent endogenous vasodilator, NO has a role in inflammation, thrombosis, immunity, and neurotransmission. Measurement of NO is important as many of its effects (e.g., vasodilatation, inhibition of platelet aggregation) are similar to those of other substances produced by the endothelium, such as prostacyclin. NO is formed in small amounts in vivo and is rapidly destroyed by interaction with oxygen, making measurement difficult. A computerized search of the past five year's literature found NO measurements reported in fewer than 50 of 955 articles dealing with EDRF. Inhibitors of NO synthesis such as the arginine analogs or agents that inactivate NO, such as reduced hemoglobin, are commonly used as specific probes for NO, in vivo and in vitro; however, none of the NO inhibitors is completely specific. The most widely used assays use one of three strategies to detect NO: 1) NO is "trapped...Continue Reading

Citations

Feb 1, 1995·Alcoholism, Clinical and Experimental Research·M L AdamsT J Cicero
Sep 1, 1996·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Z HuangM A Moskowitz
Nov 1, 1996·Physiological Measurement·T S HakimG Anderson
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·R A CohenC J Garland
Dec 31, 1997·American Journal of Respiratory and Critical Care Medicine·P T MurrayJ G Umans
Dec 12, 1997·FEBS Letters·A G McBride, G C Brown
Oct 14, 1998·American Journal of Respiratory and Critical Care Medicine·S L ArcherA T Dinh-Xuan
Nov 7, 1998·Acta Physiologica Scandinavica·M MoleroJ Chacin
Jan 16, 1999·Journal of Cardiovascular Pharmacology·S LecourL Rochette
Mar 6, 1999·The Journal of Physiology·A EscrigM Mas
Sep 25, 1999·Pediatric Pulmonology·N KissoonP E Silkoff
Feb 17, 2001·American Journal of Respiratory and Critical Care Medicine·T BuschE R Swenson
Aug 31, 2000·Pediatric Emergency Care·L R DeNicolaP E Silkoff
Feb 17, 2001·American Journal of Physiology. Heart and Circulatory Physiology·X F FigueroaM P Boric
Mar 15, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·P S AndrewS Kaufman
Sep 13, 2001·European Journal of Anaesthesiology·B MayerM Blobner
Nov 8, 2001·American Journal of Physiology. Cell Physiology·Y SongY Xia
Mar 27, 2002·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Y UekiK Eguchi
Apr 20, 2002·Journal of Pediatric Gastroenterology and Nutrition·Tryggve LjungPer M Hellström
Oct 22, 2002·American Journal of Physiology. Cell Physiology·Maria Cecilia Rodriguez-GalánSilvia Correa
Jul 17, 2003·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nathalie LaraJean-Michel Le Mellédo
May 13, 2003·Scandinavian Journal of Gastroenterology·C von BothmerL Fändriks
Feb 24, 2004·American Journal of Physiology. Gastrointestinal and Liver Physiology·Norihisa IshimuraGregory J Gores
Oct 26, 2005·Anesthesia and Analgesia·Heidrun FinkManfred Blobner
Apr 12, 2006·Current Opinion in Clinical Nutrition and Metabolic Care·Ines HardyGil Hardy
Feb 28, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Alper O KaracaliogluMehmet A Ozguven
Feb 1, 2006·Clinical and Experimental Pharmacology & Physiology·Shang Jyh KaoHsing I Chen
Feb 28, 2007·Clinical and Experimental Pharmacology & Physiology·Chain Fa SuHsing I Chen

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