Measurement of peritoneal fluid urea nitrogen and creatinine levels is useful to detect iatrogenic urinary tract leakage in colorectal surgery

Journal of the Chinese Medical Association : JCMA
Jui-Ho WangChao-Wen Hsu

Abstract

Increased peritoneal drainage after colorectal surgery is a common problem. Measurement of peritoneal fluid urea nitrogen (UN) and creatinine (Cr) is a diagnostic tool to detect the urinary tract leakage (UTL). We evaluated its application in colorectal surgery. We conducted a retrospective chart review study. We enrolled patients with iatrogenic UTL, and measured their UN and Cr levels in peritoneal fluid and compared them with those in blood and urine. Meanwhile, we assigned patients without UTL to a control group and compared clinical parameters of both groups. Twenty-three patients with iatrogenic UTL were recruited. The overall incidence was 0.5%. UN level in peritoneal fluid (322 ± 56 mg/dL) was significantly higher than that in blood (18.7 ± 4.0 mg/dL, p < 0.001); Cr level in peritoneal fluid (69.7 ± 14.3 mg/dL) was also significantly higher than that in blood (1.5 ± 0.5 mg/dL, p < 0.001). UN level in peritoneal fluid was significantly higher in the iatrogenic UTL group than in the control group (322 mL/dL vs. 9.3 mL/dL, p < 0.001); Cr level in peritoneal fluid was also significantly higher (69.7 mg/dL vs. 0.98 mg/dL, p < 0.001). When increased peritoneal drainage is found postoperatively in colorectal surgery, measureme...Continue Reading

References

May 1, 1985·Annals of Emergency Medicine·M J RubinH W Meislin
Jul 31, 1972·JAMA : the Journal of the American Medical Association·M J SullivanL H Banowsky
Jul 27, 2000·Obstetrics and Gynecology·K J Manahan, J Fanning
Jan 19, 2005·Techniques in Coloproctology·J RoseF Köckerling
Sep 12, 2006·Journal of Minimally Invasive Gynecology·Hsin-Hung WuKuo-Cherng Lin
Jun 2, 2011·Clinics in Colon and Rectal Surgery·Scott E Delacroix, J C Winters
Sep 3, 2011·Clinics in Colon and Rectal Surgery·Scott E Delacroix, J C Winters
Mar 21, 2012·Archives of Surgery·Nandini C PalaniappaCelia M Divino

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Citations

Sep 2, 2016·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Robert D WilliamsDavid D Thiel
Mar 24, 2016·Current Environmental Health Reports·Jean D Brender, Peter J Weyer
Jun 10, 2021·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Subodh Kumar RegmiBadrinath R Konety

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