Measurement of platelet aggregation peptide inhibitors by ultrasonic interferometry

Analytical Biochemistry
B ChabanceA M Fiat

Abstract

Several peptide inhibitors of thrombin- or collagen-induced platelet aggregation and of the interaction between glycoprotein Ib and von Willebrand factor were studied by a new method--ultrasonic interferometry (Echo Cell). Inhibition of aggregate formation in a concentration-dependent manner was observed. The sensitivity of the method was 3 to 40 times higher than that of classical turbidimetry.

References

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Citations

Jul 23, 2011·Food & Function·Martha Phelan, David Kerins

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