Measurement of quality of life in pediatric asthma clinical trials

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
B G Bender

Abstract

This review will provide the reader a current appraisal of attempts to measure quality of life (QoL) in pediatric asthma and guidelines toward making a discriminating selection from available QoL questionnaires. A MEDLINE literature search was performed using the index terms quality of life and asthma. Reference lists from articles identified through this search were also perused. References that did not include the term "quality of life" but clearly addressed this topic were included. Nine questionnaires employed in studies evaluating life quality associated with pediatric asthma were identified. Five of the questionnaires are parent-completed and four are child-completed. The instruments vary considerably in length and content areas, and most have been used in a single study. The science of measuring QoL change associated with pediatric asthma is in its infancy and the decision to use any single QoL instrument should be made cautiously. Investigators seeking to employ a QoL questionnaire in pediatric asthma clinical trials must consider several problems specific to evaluation with children, including age effects, reading ability, impact of adult assistance upon responses, and the inclusion of mother- versus father-completed q...Continue Reading

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Citations

Dec 19, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Marcella R PriceMary D Klinnert
Jan 5, 2002·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·S H SichererA Muñoz-Furlong
May 3, 2001·Journal of Developmental and Behavioral Pediatrics : JDBP·M T SteinR E Stein
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Oct 13, 2000·American Journal of Respiratory and Critical Care Medicine·L AsmussenK B Weiss
Oct 2, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·S van BragtT Schermer
Jul 29, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Janice P MinardM Diane Lougheed
Mar 26, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·H RaatJ C van der Wouden
Jul 22, 2004·Ambulatory Pediatrics : the Official Journal of the Ambulatory Pediatric Association·Lynn M OlsonMary Pat Frintner
Oct 14, 2004·The Journal of Pediatrics·Sande O OkeloGregory B Diette
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Jan 5, 2006·Pró-fono : revista de atualização científica·Ferreira Paula Erika AlvesFernando Freitas Ganança
Jun 5, 2003·Pediatrics·Mona E MansourThomas G DeWitt

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