Measurement of short transverse relaxation times by pseudo-echo nutation experiments

Journal of Magnetic Resonance
Maude FerrariDaniel Canet

Abstract

Very short NMR transverse relaxation times may be difficult to measure by conventional methods. Nutation experiments constitute an alternative approach. Nutation is, in the rotating frame, the equivalent of precession in the laboratory frame. It consists in monitoring the rotation of magnetization around the radio-frequency (rf) field when on-resonance conditions are fulfilled. Depending on the amplitude of the rf field, nutation may be sensitive to the two relaxation rates R1 and R2. A full theoretical development has been worked out for demonstrating how these two relaxation rates could be deduced from a simple nutation experiment, noticing however that inhomogeneity of the rf field may lead to erroneous results. This has led us to devise new experiments which are the equivalent of echo techniques in the rotating frame (pseudo spin-echo nutation experiment and pseudo gradient-echo experiment). Full equations of motion have been derived. Although complicated, they indicate that the sum of the two relaxation rates can be obtained very accurately and not altered by rf field inhomogeneity. This implies however an appropriate data processing accounting for the oscillations which are superposed to the echo decays and, anyway, theor...Continue Reading

Citations

Oct 28, 2019·Solid State Nuclear Magnetic Resonance·Nikolay Sinyavsky, Ivan Mershiev
Oct 15, 2019·Journal of Magnetic Resonance·Maude FerrariDaniel Canet

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