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Measurement of the oxime HI-6 after peripheral administration in tandem with neurotransmitter levels in striatal dialysates: effects of soman intoxication

Journal of Pharmacological and Toxicological Methods

Jun 1, 1996

Gudrun Cassel, P Fosbraey

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Abstract

In the present study, the technique of microdialysis combined with tandem high-performance liquid chromatography was used to determine the striatal levels of HI-6 and neurotransmitters following peripheral administration of HI-6 (50 mg/kg i.m.) in conscious, freely moving rats. The resu...read more

Mentioned in this Paper

Acetylthiocholinesterase
Antidote
High Pressure Liquid Chromatography Procedure
Physical Dialysis
Dose-Response Relationship, Drug
Pyridinium Compounds
Rats, Wistar
Soman
som-sim
Lentiform Nucleus Structure
Paper Details
References
  • References23
  • Citations17
123
  • References23
  • Citations17
12

Measurement of the oxime HI-6 after peripheral administration in tandem with neurotransmitter levels in striatal dialysates: effects of soman intoxication

Journal of Pharmacological and Toxicological Methods

Jun 1, 1996

Gudrun Cassel, P Fosbraey

PMID: 8782094

DOI: 10.1016/1056-8719(96)00027-5

Abstract

In the present study, the technique of microdialysis combined with tandem high-performance liquid chromatography was used to determine the striatal levels of HI-6 and neurotransmitters following peripheral administration of HI-6 (50 mg/kg i.m.) in conscious, freely moving rats. The resu...read more

Mentioned in this Paper

Acetylthiocholinesterase
Antidote
High Pressure Liquid Chromatography Procedure
Physical Dialysis
Dose-Response Relationship, Drug

Related Papers

Paper Details
References
  • References23
  • Citations17
123
  • References23
  • Citations17
12

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