PMID: 8594030Nov 1, 1995Paper

Measurement of three-dimensional lung tree structures by using computed tomography

Journal of Applied Physiology
S A WoodW Mitzner

Abstract

A method was devised to computationally segment and measure three-dimensional pulmonary trees in situ. Bronchi and pulmonary vessels were computationally extracted from volumetric computed tomography data based on radiopacity differences between airway wall and airway lumen and between blood and parenchyma, respectively. The tree was reduced to a central axis to facilitate measurement of branch segment length and angle. Cross-sectional area was measured on a reconstructed computed tomography slice perpendicular to this central axis. The method was validated by scanning two Plexiglas phantoms and an intact lung. Reconstructed diameters in the phantoms were accurate for branches > 2 mm. In the lung airway branches between 1 and 2 mm in diameter were often unresolved when their angle of orientation with respect to the axis of the scanner was > 45 degrees. However, if a branch was resolved, its reconstructed diameter was little affected by orientation. This method represents a significant improvement in the analysis of complex pulmonary structures in three dimensions.

Citations

Mar 31, 2005·Physics in Medicine and Biology·Ashutosh Chaturvedi, Zhenghong Lee
Feb 19, 2005·Journal of Applied Physiology·Robert H BrownWayne Mitzner
Mar 25, 2006·American Journal of Respiratory and Critical Care Medicine·Masaru HasegawaMasaharu Nishimura
Oct 12, 2007·Clinical Medicine. Circulatory, Respiratory and Pulmonary Medicine·Robert BrownWayne Mitzner
Dec 14, 2011·Clinical Physiology and Functional Imaging·Jae Seung LeeSang-Do Lee
Sep 21, 2016·Critical Reviews in Food Science and Nutrition·M M RahmanM A Karim
Apr 17, 2020·Journal of Applied Physiology·Dragoş M VasilescuJames C Hogg
Aug 24, 2000·Journal of Applied Physiology·R H Brown, W Mitzner
Aug 22, 2001·American Journal of Physiology. Heart and Circulatory Physiology·K L KarauC A Dawson
Nov 22, 2001·Journal of Applied Physiology·R H Brown, W Mitzner
Mar 2, 1999·American Journal of Respiratory and Critical Care Medicine·G G KingP D Paré
Oct 20, 2001·Journal of Applied Physiology·R Brown, W Mitzner
Jan 5, 2002·Proceedings of the National Academy of Sciences of the United States of America·Landon S KingRobert H Brown
Feb 13, 2001·Physiological Genomics·W MitznerW Lee
Nov 16, 2001·American Journal of Physiology. Heart and Circulatory Physiology·K L KarauC A Dawson
Mar 1, 2008·Journal of Applied Physiology·Robert H BrownWayne Mitzner
Mar 1, 2008·Experimental Lung Research·Harald GroebenWayne Mitzner
Jun 21, 2011·Lung·Caterina SalitoAndrea Aliverti
Oct 15, 2009·Journal of Digital Imaging·Giorgio De NunzioPiernicola Oliva
Dec 26, 2001·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·B K HanK M Yeon
May 20, 2003·Journal of Applied Physiology·Osama I SabaJoseph M Reinhardt
May 27, 2003·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Robert H Brown, Wayne Mitzner
Feb 15, 2000·American Journal of Respiratory and Critical Care Medicine·G G KingP D Paré
Dec 9, 2000·American Journal of Respiratory and Critical Care Medicine·R H Brown, W Mitzner
Jul 21, 2007·Respiration; International Review of Thoracic Diseases·Geoffrey McLennanEric A Hoffman
Apr 26, 2007·Anesthesia and Analgesia·Herng-Yu Sucie ChangRobert H Brown
Aug 1, 2012·International Journal of Computer Assisted Radiology and Surgery·L VerscheureM Vermandel
Dec 8, 2011·Journal of Korean Medical Science·Jung-Wan YooSang-Do Lee
Apr 19, 2005·Radiology·Patrick BergerFrançois Laurent
Jul 12, 2018·Physics in Medicine and Biology·Z BianB van Ginneken
May 12, 2000·American Journal of Respiratory and Critical Care Medicine·W Mitzner, R H Brown
Dec 8, 1998·Journal of Applied Physiology·R H Brown, W Mitzner
Dec 25, 2010·Annals of Biomedical Engineering·Vanessa J KellyBruce R Thompson
Jul 1, 2009·Wiley Interdisciplinary Reviews. Systems Biology and Medicine·Merryn H TawhaiChing-Long Lin
Sep 21, 2012·Radiology·Maxime HackxPierre Alain Gevenois

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