Measurements of the effect of membrane asymmetry on the mechanical properties of lipid bilayers

Chemical Communications : Chem Comm
Yuval ElaniOscar Ces

Abstract

We detail an approach for constructing asymmetric membranes and characterising their mechanical properties, leading to the first measurement of the effect of asymmetry on lipid bilayer mechanics. Our results demonstrate that asymmetry induces a significant increase in rigidity compared to symmetric membranes. Given that all biological membranes are asymmetric our findings have profound implications for the role of this phenomenon in biology.

References

Nov 1, 1973·Zeitschrift Für Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie·W Helfrich
Oct 10, 1998·Biochemical Society Transactions·G S AttardS Jackowski
Jun 27, 2000·Biophysical Journal·W RawiczE Evans
Jul 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·G S AttardS Jackowski
Sep 14, 2000·Biochimica Et Biophysica Acta·P J Booth
Jan 19, 2002·Critical Reviews in Biochemistry and Molecular Biology·P J BoothM Lorch
Apr 5, 2002·Medicinal Research Reviews·J Middleton Boon, Bradley D Smith
Sep 2, 2003·Current Opinion in Structural Biology·Eduardo Perozo, Douglas C Rees
Sep 10, 2003·Proceedings of the National Academy of Sciences of the United States of America·Sophie PautotD A Weitz
Mar 3, 2004·Proceedings of the National Academy of Sciences of the United States of America·Heedeok Hong, Lukas K Tamm
Apr 23, 2004·The European Physical Journal. E, Soft Matter·J PécréauxP Bassereau
Jun 29, 2004·European Biophysics Journal : EBJ·Jonas HenriksenJohn H Ipsen
Dec 14, 2004·Proceedings of the National Academy of Sciences of the United States of America·Vincent Noireaux, Albert Libchaber
Jul 5, 2005·Current Opinion in Structural Biology·Paula J Booth
Oct 19, 2006·Chemistry and Physics of Lipids·Derek Marsh
Nov 15, 2006·Cellular and Molecular Life Sciences : CMLS·T Pomorski, A K Menon
Nov 30, 2006·The Journal of Biological Chemistry·David L Daleke
Jan 25, 2008·Nature Reviews. Molecular Cell Biology·Gerrit van MeerGerald W Feigenson
Apr 15, 2008·Journal of the American Chemical Society·William L HwangHagan Bayley
Jun 21, 2008·Journal of Molecular Biology·Annela M SeddonPaula J Booth
Nov 6, 2008·The Journal of Physical Chemistry. B·Tsutomu HamadaMasahiro Takagi
Nov 27, 2008·BMC Biochemistry·Kalypso CharalambousPaula J Booth
Aug 25, 2009·Journal of Molecular Biology·David MillerPaula J Booth
Jan 2, 2010·FEBS Letters·F-Xabier ContrerasFélix M Goñi
Feb 23, 2010·Proceedings of the National Academy of Sciences of the United States of America·Paula J Booth, Jane Clarke
Mar 26, 2010·Chembiochem : a European Journal of Chemical Biology·Peter WaldePasquale Stano
Jul 8, 2010·Current Opinion in Cell Biology·Todd R Graham, Michael M Kozlov
Feb 12, 2011·Journal of the American Chemical Society·Sandro Matosevic, Brian M Paegel
Feb 15, 2011·Proceedings of the National Academy of Sciences of the United States of America·Vincent NoireauxAlbert Libchaber
Apr 1, 2011·ACS Applied Materials & Interfaces·Peichi C HuNoah Malmstadt
Jan 21, 2012·Bio Systems·Pasquale StanoPier Luigi Luisi
Mar 21, 2012·Journal of the American Chemical Society·Kalypso CharalambousOscar Ces
Jun 13, 2012·Chembiochem : a European Journal of Chemical Biology·Paolo CarraraPier Luigi Luisi
Apr 13, 2013·Nanotechnology·Zhenhai ZhangZhiguo Shi
Oct 25, 2013·Nature Chemistry·Sandro Matosevic, Brian M Paegel
Dec 4, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Maik HadornTetsuya Yomo
Mar 29, 2014·Advances in Colloid and Interface Science·Rumiana Dimova
Mar 29, 2014·Soft Matter·Benjamin KollmitzerGeorg Pabst

❮ Previous
Next ❯

Citations

May 2, 2015·Physical Chemistry Chemical Physics : PCCP·Yuval ElaniOscar Ces
Apr 30, 2016·Langmuir : the ACS Journal of Surfaces and Colloids·Frederick A HeberleGeorg Pabst
Nov 11, 2016·Lab on a Chip·Nathan E BarlowOscar Ces
Jan 18, 2017·Chemistry : a European Journal·Ana Isabel Perez JimenezOlivier Buriez
Jun 29, 2017·ACS Nano·Tatiana TrantidouOscar Ces
Mar 25, 2018·Advanced Materials·Joe ForthThomas P Russell
Sep 3, 2017·European Biophysics Journal : EBJ·Paolo PengoPaola Posocco
Jan 24, 2019·Lab on a Chip·Laura R ArriagaDavid A Weitz
Mar 5, 2019·Advanced Materials·Joe ForthThomas P Russell
Nov 23, 2018·Journal of the Royal Society, Interface·Nathan E BarlowOscar Ces
Sep 19, 2019·Chembiochem : a European Journal of Chemical Biology·Akanksha MogaTom Robinson
Oct 17, 2019·Frontiers in Cell and Developmental Biology·Arwen I I TylerSowmya Purushothaman
Mar 7, 2019·Proceedings of the National Academy of Sciences of the United States of America·Miaorong YuHuajian Gao
Jun 17, 2020·Soft Matter·James W CarterFernando Bresme
Aug 2, 2017·Scientific Reports·Masayuki Iwamoto, Shigetoshi Oiki
Apr 5, 2017·Proceedings of the National Academy of Sciences of the United States of America·Marion KochJake Baum
Oct 14, 2017·FEMS Microbiology Reviews·Katrin RosenthalAndreas Schmid
Oct 13, 2019·Nature Communications·Jan N GalleJohannes H Hegemann
May 20, 2018·Physical Review. E·Adarsh K ChaurasiaEric C Freeman
May 6, 2019·Micromachines·Pashiini SupramaniamAli Salehi-Reyhani
Dec 16, 2018·Nature Communications·Anaïs MennyDoryen Bubeck
Jan 20, 2020·Biophysical Journal·Amirali Hossein, Markus Deserno
Feb 6, 2020·Biophysical Journal·Edward Lyman, Alexander J Sodt
Nov 6, 2018·Biophysical Journal·John J Williamson, Peter D Olmsted
Jul 18, 2021·Biophysical Journal·Nestor Lopez MoraPaula J Booth
Aug 28, 2021·Nano Letters·Joe ForthThomas P Russell

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.