Abstract
There is still no standardized measure of left ventricular (LV) dyssynchrony or definition of response in candidates of cardiac resynchronization therapy (CRT). Recipients of CRT underwent echocardiographic assessment of LV dyssynchrony before and immediately after implantation of a CRT device. Patients were followed for 6 months postimplantation. A total of 44 patients (64 +/- 12 years, 30 men, and 26 with ischemic cardiomyopathy) were included in this analysis. There was a significant decrease in both radial (304 +/- 137 vs 121 +/- 85 ms, p <0.001) and longitudinal (143 +/- 104 vs 95 +/- 43 ms, p = 0.02) measures of LV dyssynchrony immediately after CRT. The immediate post-CRT change in radial (r = -0.43, p = 0.015) but not longitudinal (r = -0.09, p = 0.61) LV dyssynchrony correlated with a significant improvement in the physical component of the quality-of-life score 6 months after CRT. Although a higher baseline longitudinal (p = 0.05) or radial (p = 0.025) LV dyssynchrony predicted a >or=1 improvement in New York Heart Association classification of heart failure 6 months after CRT, acute changes in neither radial (p = 0.71) nor longitudinal (p = 0.89) LV dyssynchrony were predictive of any improved echocardiographic outco...Continue Reading
References
Jan 30, 2002·Circulation·Cheuk-Man YuChu-Pak Lau
May 28, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Shimon A ReisnerZvi Friedman
Sep 29, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Marina LeitmanZvi Vered
Nov 3, 2004·Journal of the American College of Cardiology·Jeroen J BaxMartin J Schalij
Jan 31, 2006·The American Journal of Cardiology·Gabe B BleekerCheuk-Man Yu
Feb 16, 2006·Circulation·Matthew S SuffolettoJohn Gorcsan
Oct 9, 2007·Journal of the American College of Cardiology·John GorcsanJeroen J Bax
Citations
Jun 22, 2010·Journal of Cardiopulmonary Rehabilitation and Prevention·Karin F HothRonald A Cohen
Jan 15, 2011·Cardiology Research and Practice·Suman S KuppahallyDavid Liang
Dec 5, 2009·The International Journal of Cardiovascular Imaging·Kenji KitaizumiMasakazu Kohno
Aug 10, 2012·The International Journal of Cardiovascular Imaging·Razi KhanJames A White
Jul 3, 2013·Current Cardiology Reports·Jeffrey LiuSamir Saba
Aug 15, 2014·Scandinavian Cardiovascular Journal : SCJ·Gani BajraktariMichael Y Henein
Jun 15, 2010·International Journal of Cardiology·Yanlan HuangNan Qu
Aug 26, 2009·Pacing and Clinical Electrophysiology : PACE·Henneke VersteegSusanne S Pedersen
May 15, 2009·Echocardiography·Salvatore CostaRobert Palac
Jan 28, 2014·European Journal of Heart Failure·Henneke VersteegMathias Meine
Aug 9, 2011·The American Journal of Cardiology·Henneke VersteegSusanne S Pedersen
Oct 17, 2014·Pacing and Clinical Electrophysiology : PACE·Radosław LenarczykZbigniew Kalarus
Dec 2, 2009·Korean Circulation Journal·Jum Suk KoJung Chaee Kang
Dec 18, 2008·European Journal of Clinical Investigation·F WiesbauerT Binder