Measuring fatigue as a symptom in COPD: From descriptors and questionnaires to the importance of the problem

Chronic Respiratory Disease
Sabina Antonela Antoniu, Didona Ungureanu

Abstract

Fatigue is a symptom commonly diagnosed in cancers and in many other chronic debilitating diseases and is one of the main therapeutic targets for various pharmacologic and non-pharmacologic interventions. However, in chronic obstructive pulmonary disease (COPD), this symptom, which can be considered as the main extrapulmonary clinical feature of the disease, can impact significantly on the health-related quality of life of the patients. The aims of this review are to discuss the issues related to fatigue assessment in COPD and to highlight the importance of this symptom in this setting based on the data retrieved from articles published between 1987 through August 2014 available on MEDLINE database. Fatigue can be measured by various scales or questionnaires that are designed for generic purposes or for COPD-related purposes but is still underdiagnosed and undertreated. This is due to the fact that its clinical and prognostic relevance are not appropriately acknowledged. The early identification of fatigue clinical descriptors from patients' reports could help with better management of this symptom.

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Citations

Feb 24, 2016·Journal of Pain and Symptom Management·Vivi Lycke ChristensenTone Rustøen
Mar 12, 2016·Expert Review of Pharmacoeconomics & Outcomes Research·Sabina Antonela Antoniu, Lucian Vasile Boiculese
Nov 26, 2015·Therapeutic Advances in Respiratory Disease·Sabina Antonela AntoniuLucian Boiculese
Jun 8, 2018·European Respiratory Review : an Official Journal of the European Respiratory Society·Sarah Houben-WilkeFrits M E Franssen
Apr 16, 2021·European Respiratory Review : an Official Journal of the European Respiratory Society·Zjala EbadiJeannette B Peters
Jul 22, 2021·Pulmonology·Carla SimonelliNicolino Ambrosino
May 18, 2021·Revista Clínica Espanõla·M Gericó Aseguinolaza, J Díez-Manglano

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