Measuring length-tension function of the anal sphincters and puborectalis muscle using the functional luminal imaging probe

American Journal of Physiology. Gastrointestinal and Liver Physiology
Lori J TuttleRavinder K Mittal

Abstract

The functional luminal imaging probe (FLIP) has been used to measure the distensibility of the anal canal. We hypothesized that with increasing distension of the anal canal with FLIP there will be an increase in length of the anal sphincter muscle allowing measurement of the length-tension function of anal sphincter and puborectalis muscles (PRM). We studied 14 healthy nulliparous women. A custom-designed FLIP bag (30-mm diameter) was placed in the vagina and then in the anal canal, distended in 10-ml steps with volumes ranging from 30 to 90 ml. At each volume, subject performed maximal voluntary squeezes. Length-tension measurements were also made with a manometric probe system. Tension was calculated (pressure × radius) in Newtons per meter using a custom software program. Peak tensions at different FLIP volumes were compared with the manometric data. No change in the luminal CSA was noted at low fluid volumes; the sphincter muscles were able to fully collapse the FLIP bag within the anal canal/vagina even at rest. At larger volumes, with each squeeze there was an increase in the bag pressure and reduction in the cross-sectional area, which represents concentric contraction of the muscle. Both rest and squeeze tension increas...Continue Reading

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Citations

Sep 10, 2019·Journal of Digestive Diseases·Hui Min ChenQiang Cai
Aug 29, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Charlotte DesprezGuillaume Gourcerol
Nov 19, 2019·American Journal of Physiology. Gastrointestinal and Liver Physiology·Ali ZifanLori J Tuttle

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Software Mentioned

FLIP
Matlab

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