Measuring Myocardial Energetics with Cardiovascular Magnetic Resonance Spectroscopy

Heart Failure Clinics
Joevin SourdonRobert G Weiss

Abstract

The heart has the highest energy demands per gram of any organ in the body and energy metabolism fuels normal contractile function. Metabolic inflexibility and impairment of myocardial energetics occur with several common cardiac diseases, including ischemia and heart failure. This review explores several decades of innovation in cardiac magnetic resonance spectroscopy modalities and their use to noninvasively identify and quantify metabolic derangements in the normal, failing, and diseased heart. The implications of this noninvasive modality for predicting significant clinical outcomes and guiding future investigation and therapies to improve patient care are discussed.

References

Dec 15, 1979·The Biochemical Journal·P B GarlickP J Seeley
Jun 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P A BottomleyP B Roemer
Oct 24, 1985·The New England Journal of Medicine·J S IngwallP D Allen
May 1, 1988·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A M KellerP J Cannon
Jun 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·M J BlackledgeG K Radda
Dec 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·P A BottomleyR W Redington
May 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P A BottomleyR G Weiss
Oct 15, 1996·Circulation·L NascimbenP D Allen
May 15, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M OkadaM Kinoshita
May 20, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M MeiningerM von Kienlin
Oct 25, 2000·American Journal of Physiology. Heart and Circulatory Physiology·V P ChackoR G Weiss
Jun 18, 2003·Circulation·Michaela Scheuermann-FreestoneKieran Clarke
Aug 22, 2003·Proceedings of the National Academy of Sciences of the United States of America·Jan H Ardenkjaer-LarsenKlaes Golman
Feb 1, 1951·Medicine·R E OLSON, W B SCHWARTZ
Nov 4, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Saumya SharmaHeinrich Taegtmeyer
Jan 14, 2005·Proceedings of the National Academy of Sciences of the United States of America·Robert G WeissPaul A Bottomley
May 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Ichiro NakaeMinoru Horie
Jun 24, 2005·American Journal of Physiology. Endocrinology and Metabolism·Jason S ReingoldLidia S Szczepaniak
Jul 1, 2005·Physiological Reviews·William C StanleyGary D Lopaschuk
Jan 18, 2006·The Journal of Physiology·Valdur SaksTheo Wallimann
Mar 16, 2007·The New England Journal of Medicine·Stefan Neubauer
Nov 22, 2007·The Journal of Clinical Endocrinology and Metabolism·Sebastiaan HammerJohannes A Romijn
Apr 23, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Klaes GolmanSven Månsson
Mar 31, 2009·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Marie A SchroederDamian J Tyler
Jun 1, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Michael SchärPaul A Bottomley

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Citations

May 14, 2021·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Joevin SourdonStanislas Rapacchi

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