PMID: 8591065Nov 1, 1995Paper

Measuring the effects of antihypertensive therapy upon the quality of life

Current Opinion in Nephrology and Hypertension
A Fletcher

Abstract

After an explosion of interest at the beginning of the 1990s in measuring quality of life in hypertensive patients, the past few years have seen relatively few studies in this area. This is partly because when new drugs were compared, in general, no clear advantage was observed for any particular drug or class of antihypertensive. More recently the emphasis on choosing antihypertensive treatments that have been shown to be effective in reducing cardiovascular morbidity and mortality, as well as constraints on resources, have focused attention on older drugs such as diuretics. Only a few trials have measured quality of life on a diuretic, but the largest and most powerful of these found no evidence that diuretics impair quality of life.

Citations

Oct 12, 2000·Journal of the American College of Cardiology·P Pibarot, J G Dumesnil
Feb 13, 2001·Journal of Clinical Epidemiology·C Bardage, D G Isacson
Jul 28, 1999·Clinical and Experimental Hypertension : CHE·J WhitworthD Henry
Aug 26, 2010·Journal of Advanced Nursing·Luciana C PalharesRoberta C M Rodrigues
May 12, 2005·The Journal of Clinical Hypertension·Joel Handler
Apr 1, 2007·Expert Review of Pharmacoeconomics & Outcomes Research·Mohsen Asadi-Lari, David Gray

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