Measuring the hypnotic depth of anaesthesia based on the EEG signal using combined wavelet transform, eigenvector and normalisation techniques

Computers in Biology and Medicine
Tai Nguyen-KyMel Malan

Abstract

This paper presents a new index to measure the hypnotic depth of anaesthesia (DoA) using EEG signals. This index is derived from applying combined Wavelet transform, eigenvector and normalisation techniques. The eigenvector method is first applied to build a feature function for six levels of coefficients in a discrete wavelet transform (DWT). The best Daubechies wavelet and their ranking value p are optimally determined to identify different states of anaesthesia. A statistic normalisation process is then carried out to re-scale data and compute the hypnotic depth of anaesthesia. Finally, a new function ZDoA is proposed to compute a DoA index which corresponds one of the five depths of anaesthesia states to very deep anaesthesia, deep anaesthesia, moderate anaesthesia, light anaesthesia and awake. Simulation results based on real anaesthetised EEGs demonstrate that the new index generally parallels the BIS index. In particular, the ZDoA index is often faster than the BIS index to react to the transition period between consciousness and unconsciousness for this data set. A Bland-Altman plot indicates a 95.23% agreement between the ZDoA and BIS indices. The ZDoA trend is responsive, and its movement is consistent with the clinic...Continue Reading

References

Jun 12, 1998·British Journal of Anaesthesia·J D Hall, G G Lockwood
Oct 20, 1998·Anesthesiology·I J Rampil
Feb 11, 2004·European Journal of Anaesthesiology·G SchneiderE Kochs
Jun 15, 2004·British Journal of Anaesthesia·S KreuerW Wilhelm
Aug 31, 2004·Anesthesia and Analgesia·Peter S SebelKaren B Domino
May 11, 2005·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Dabao ZhangWilliam E Fry
Apr 11, 2006·IEEE Transactions on Bio-medical Engineering·Tatjana ZikovCraig R Ries
Apr 26, 2006·Best Practice & Research. Clinical Anaesthesiology·David Drover, H R Ortega
Jun 6, 2006·British Journal of Anaesthesia·J BruhnM M R F Struys
Jul 3, 2010·IEEE Transactions on Bio-medical Engineering·T Nguyen-KyYan Li
May 25, 2011·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Tai Nguyen-KyRobert Gray

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Citations

Jan 7, 2016·Australasian Physical & Engineering Sciences in Medicine·Shuaifang WangDavid Lai
Jul 18, 2021·Neural Networks : the Official Journal of the International Neural Network Society·B Orkan OlcayBilge Karaçalı

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