Measuring venous oxygenation using the photoplethysmograph waveform.

Journal of Clinical Monitoring and Computing
Zachary D WaltonKirk H Shelley

Abstract

We investigate the hypothesis that the photoplethysmograph (PPG) waveform can be analyzed to infer regional venous oxygen saturation. Fundamental to the successful isolation of the venous saturation is the identification of PPG characteristics that are unique to the peripheral venous system. Two such characteristics have been identified. First, the peripheral venous waveform tends to reflect atrial contraction. Second, ventilation tends to move venous blood preferentially due to the low pressure and high compliance of the venous system. Red (660 nm) and IR (940 nm) PPG waveforms were collected from 10 cardiac surgery patients using an esophageal PPG probe. These waveforms were analyzed using algorithms written in Mathematica. Four time-domain saturation algorithms (ArtSat, VenSat, ArtInstSat, VenInstSat) and four frequency-domain saturation algorithms (RespDC, RespAC, Cardiac, and Harmonic) were applied to the data set. Three of the algorithms for calculating venous saturation (VenSat, VenInstSat, and RespDC) demonstrate significant difference from ArtSat (the conventional time-domain algorithm for measuring arterial saturation) using the Wilcoxon signed-rank test with Bonferroni correction (p < 0.0071). This work introduces ne...Continue Reading

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Oct 22, 2009·Current Opinion in Anaesthesiology·Richa Wardhan, Kirk Shelley

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Citations

Dec 7, 2014·Best Practice & Research. Clinical Anaesthesiology·Aymen A Alian, Kirk H Shelley
Aug 20, 2015·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Karsten Bartels, Robert H Thiele
May 27, 2011·Anesthesia and Analgesia·Robert H ThieleMarcel E Durieux
Sep 15, 2015·Physiological Measurement·K ShafqatP A Kyriacou
May 23, 2013·Anesthesiology·Kirk H ShelleyAdam J Shelley
Nov 23, 2016·Journal of Clinical Monitoring and Computing·A M BelhajR M Langford
May 21, 2017·Biomedical Engineering Online·Musabbir KhanJ Geoffrey Chase
Dec 1, 2017·Biomedical Optics Express·Kfir AkonsDvir Yelin
Jul 1, 2019··Intisar Rizwan I. HaqueTahir Zaidi

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