Mechanical chest compressions improved aspects of CPR in the LINC trial

Resuscitation
Alexander EsibovSten Rubertsson

Abstract

We studied resuscitation process metrics in patients with out-of-hospital cardiac arrest enrolled in a randomized trial comparing one protocol designed to best use a mechanical CPR device, with another based on the 2005 European Resuscitation Council guidelines for manual CPR. We analyzed clinical data, ECG signals, and transthoracic impedance signals for a subset of the patients in the LUCAS in Cardiac Arrest (LINC) trial, including 124 patients randomized to mechanical and 82 to manual CPR. Chest compression fraction (CCF) was defined as the fraction of time during cardiac arrest that chest compressions were administered. Patients in the mechanical CPR group had a higher CCF than those in the manual CPR group [0.84 (0.78, 0.91) vs. 0.79 (0.70, 0.86), p < 0.001]. The median duration of their pauses for defibrillation was also shorter [0 s (0, 6.0) vs. 10.0 s (7.0, 14.3), p < 0.001]. Compressions were interrupted for a median of 36.0 s to apply the compression device. There was no difference between groups in duration of the longest pause in compressions [32.5s vs. 26.0 s, p = 0.24], number of compressions received per minute [86.5 vs. 88.3, p = 0.47], defibrillation success rate [73.2% vs. 81.0%, p = 0.15], or refibrillation r...Continue Reading

References

Jan 20, 2005·JAMA : the Journal of the American Medical Association·Lars WikPetter Andreas Steen
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Feb 12, 2014·Resuscitation·Sheldon CheskesUNKNOWN Resuscitation Outcomes Consortium (ROC) investigators

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Citations

Nov 26, 2015·The American Journal of Emergency Medicine·Norman A Paradis
Sep 28, 2015·Resuscitation·Abhishek Bhardwaj, Benjamin S Abella
Apr 15, 2016·Current Opinion in Critical Care·Charles D Deakin, Rudolph W Koster
Apr 8, 2016·Current Opinion in Critical Care·Sten Rubertsson
Oct 21, 2016·The American Journal of Emergency Medicine·Lukasz SzarpakOliver Robak
May 31, 2018·Critical Care : the Official Journal of the Critical Care Forum·Kurtis PooleGavin D Perkins
Jan 5, 2021·Journal of the American College of Emergency Physicians Open·David H Cisewski, Nicholas Caputo
Jan 5, 2021·Journal of the American College of Emergency Physicians Open·Michael LevyBjarne Madsen Hardig
Nov 14, 2020·Resuscitation·Samuel A Tisherman
Mar 29, 2021·Resuscitation·Jasmeet SoarJerry P Nolan
Jun 15, 2021·Notfall & Rettungsmedizin·Jasmeet SoarJerry P Nolan
Oct 28, 2021·Praxis·Luca OechslinChristophe Wyss

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