Mechanical Circulatory Support of the Right Ventricle for Adult and Pediatric Patients With Heart Failure

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Steven G ChopskiAmy L Throckmorton

Abstract

The clinical implementation of mechanical circulatory assistance for a significantly dysfunctional or failing left ventricle as a bridge-to-transplant or bridge-to-recovery is on the rise. Thousands of patients with left-sided heart failure are readily benefitting from these life-saving technologies, and left ventricular failure often leads to severe right ventricular dysfunction or failure. Right ventricular failure (RVF) has a high rate of mortality caused by the risk of multisystem organ failure and prolonged hospitalization for patients after treatment. The use of a blood pump to support the left ventricle also typically results in an increase in right ventricular preload and may impair right ventricular contractility during left ventricular unloading. Patients with RVF might also suffer from severe pulmonary dysfunction, cardiac defects, congenital heart disease states, or a heterogeneity of cardiophysiologic challenges because of symptomatic congestive heart failure. Thus, the uniqueness and complexity of RVF is emerging as a new domain of significant clinical interest that motivates the development of right ventricular assist devices. In this review, we present the current state-of-the-art for clinically used blood pumps...Continue Reading

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Citations

Apr 4, 2019·Pulmonary Circulation·Xianfeng RenWei Dong Gao
Mar 23, 2021·Interventional Cardiology Clinics·Akbarshakh Akhmerov, Danny Ramzy
Jul 17, 2021·Interactive Cardiovascular and Thoracic Surgery·Ruslan NatanovChristian Kühn

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