Mechanical complications in patients with ST-segment elevation myocardial infarction: A single centre experience

PloS One
Jonas LanzThomas Pilgrim

Abstract

The study aims to assess characteristics and outcomes of patients suffering a mechanical complication (MC) after ST-segment elevation myocardial infarction (STEMI) in a contemporary cohort of patients in the percutaneous coronary intervention era. This retrospective single-center cohort study encompasses 2508 patients admitted with STEMI between March 9, 2009 and June 30, 2014. A total of 26 patients (1.1%) suffered a mechanical complication: ventricular septal rupture (VSR) in 17, ventricular free wall rupture (VFWR) in 2, a combination of VSD and VFWR in 2, and papillary muscle rupture (PMR) in 5 patients. Older age (74.5 ± 10.4 years versus 63.9 ± 13.1 years, p < 0.001), female sex (42.3% versus 23.3%, p = 0.034), and a longer latency period between symptom onset and angiography (> 24h: 42.3% versus 16.2%, p = 0.002) were more frequent among patients with MC as compared to patients without MC. The majority of MC patients had multivessel disease (77%) and presented in cardiogenic shock (Killip class IV: 73.1%). Nine patients (7 VSR, 2 VFWR & VSR) were treated conservatively and died. Out of the remaining 10 VSR patients, four underwent surgery, three underwent implantation of an occluder device, and another three patients had...Continue Reading

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Citations

Sep 5, 2020·American Journal of Physiology. Heart and Circulatory Physiology·Anis HannaNikolaos G Frangogiannis
May 18, 2021·International Heart Journal·Riku AraiYasuo Okumura
Jun 16, 2021·Circulation·Abdulla A DamlujiUNKNOWN American Heart Association Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Cou
Aug 17, 2021·Current Opinion in Cardiology·Ali Fatehi HassanabadImtiaz S Ali

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Methods Mentioned

BETA
coronary artery bypass

Clinical Trials Mentioned

NCT02241291

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