Mechanical effects of airway humidification devices in difficult to wean patients

Critical Care Medicine
C GiraultGuy Bonmarchand

Abstract

To evaluate the influence of airway humidification devices on the efficacy of ventilation in difficult to wean patients. A prospective, randomized, controlled physiologic study. A 22-bed medical intensive care unit in a university hospital. Chronic respiratory failure patients. Performances of a heated humidifier and a heat and moisture exchanger were evaluated on diaphragmatic muscle activity, breathing pattern, gas exchange, and respiratory comfort during weaning from mechanical ventilation by using pressure support ventilation. Eleven patients with chronic respiratory failure were submitted to four pressure support ventilation sequences by using the heated humidifier and the heat and moisture exchanger at two different levels of pressure support ventilation (7 and 15 cm H(2)O). Compared with the heated humidifier and regardless of the pressure support ventilation level used, the heat and moisture exchanger significantly increased all of the inspiratory effort variables (inspiratory work of breathing expressed in J/L and J/min, pressure time product, changes in esophageal pressure, and transdiaphragmatic pressure; p <.05) and dynamic intrinsic positive end-expiratory pressure (p <.05). Similarly, the heat and moisture exchang...Continue Reading

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Citations

Jun 4, 2008·Intensive Care Medicine·Karen E A BurnsMartin R Lessard
Mar 31, 2010·Intensive Care Medicine·Belén CabelloJordi Mancebo
Sep 29, 2011·Intensive Care Medicine·Indalecio MoránJordi Mancebo
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